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ADHD Attention Deficit and Hyperactivity Disorders

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01-11-2010 | Original Article

Methylphenidate and if-then plans are comparable in modulating the P300 and increasing response inhibition in children with ADHD

Authors: I. Paul-Jordanov, M. Bechtold, C. Gawrilow

Published in: ADHD Attention Deficit and Hyperactivity Disorders | Issue 3/2010

Abstract

A disturbed functioning of the prefrontal cortex, the anterior cingulate cortex, and an accordingly reduced P300 presumably underlies executive function deficits of children with attention deficit hyperactivity disorder (ADHD). Using a combined classification and Go/NoGo task paradigm, the present study investigated whether medication with methylphenidate (MPH) modulates the P300 as measured by a high-density electroencephalogram (EEG) and facilitates response inhibition in children with ADHD. Further, effects of MPH were compared with effects of self-regulation by if-then plans (Gollwitzer in Am Psychol 54: 493–503, 1999). MPH as well as if-then plans modulated the P300 and improved inhibition of an unwanted response on a Go/NoGo task to the same level observed in children without ADHD. Importantly, self-regulation strategies might be a valuable alternative to medication with MPH in children with ADHD.

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Title: Methylphenidate and if-then plans are comparable in modulating the P300 and increasing response inhibition in children with ADHD
Authors: I. Paul-Jordanov
M. Bechtold
C. Gawrilow
Publication date: 01-11-2010
Publisher: Springer Vienna
Published in: ADHD Attention Deficit and Hyperactivity Disorders / Issue 3/2010
Print ISSN: 1866-6116
Electronic ISSN: 1866-6647
DOI: https://doi.org/10.1007/s12402-010-0028-9

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