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Acta Diabetologica
Published in: Acta Diabetologica 9/2019

01-09-2019 | Metformin | Letter to the Editor

Reply to Josef Finsterer “MELAS requires broad clinical and genetic work-up”

Authors: C. Cosentino, M. Contento, M. Paganini, E. Mannucci, B. Cresci

Published in: Acta Diabetologica | Issue 9/2019

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Excerpt

We thank Dr Finsterer for his interest in our work [1] and for his precise comments [2]. First of all, we want to emphasize the fact that our paper highlighted a potential useful therapy in treating diabetes in MELAS, so that the clinical neurological environment was duly mentioned but does not represent the main focus of the article. …
Literature
1.
2.
Finsterer J. MELAS requires broad clinical and genetic work-up ACDI-D-19-00183
3.
DeFronzo RA, Barzilai N, Simonson DC (1991) Mechanism of metformin action in obese and lean noninsulin-dependent diabetic subjects. J Clin Endocrinol Metab 73(6):1294–1301CrossRefPubMed
4.
5.
Gorman GS, Schaefer AM, Ng Y et al (2015) Prevalence of nuclear and mitochondrial DNA mutations related to adult mitochondrial disease. Ann Neurol 77(5):753–759CrossRefPubMedPubMedCentral
Metadata
Title
Reply to Josef Finsterer “MELAS requires broad clinical and genetic work-up”
Authors
C. Cosentino
M. Contento
M. Paganini
E. Mannucci
B. Cresci
Publication date
01-09-2019
Publisher
Springer Milan
Published in
Acta Diabetologica / Issue 9/2019
Print ISSN: 0940-5429
Electronic ISSN: 1432-5233
DOI
https://doi.org/10.1007/s00592-019-01361-2

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