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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 2/2020

01-02-2020 | Metastasis | ASO Author Reflections

ASO Author Reflections: Melanoma Patients with a Local Recurrence or In-Transit Metastasis: Sentinel Node Biopsy to Identify Those at Highest Risk of Metastases and Death

Authors: Amanda A. G. Nijhuis, MD, Omgo E. Nieweg, MD

Published in: Annals of Surgical Oncology | Issue 2/2020

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Excerpt

Of patients with melanoma, 2–5% will develop a local recurrence and about 4% an in-transit metastasis (ITM). These patients have a grim prognosis, as they have a high risk of further (distant) metastases. In the past, only local treatment options were available. Local recurrences and ITMs are generally excised. If the disease progresses or if excision is not an option, a range of other local–regional treatment modalities are available including cryotherapy, electrocoagulation, intralesional or topical drug administration, electrochemotherapy, laser therapy, radiotherapy, isolated limb perfusion, and isolated limb infusion. …
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Yao KA, Hsueh EC, Essner R, Foshag LJ, Wanek LA, Morton DL. Is sentinel lymph node mapping indicated for isolated local and in-transit recurrent melanoma? Ann Surg. 2003;238:743–7.CrossRef
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Beasley GM, Hu Y, Youngwirth L, Scheri RP, Salama AK, Rossfeld K, et al. Sentinel lymph node biopsy for recurrent melanoma: a multicenter study. Ann Surg Oncol. 2017;24:2728–33.CrossRef
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Gipponi M, Solari N, Giovinazzo D, Queirolo P, Bertoglio S, Villa G, et al. The role of sentinel lymph node biopsy in patients with local recurrence or in-transit metastasis of melanoma. Anticancer Res. 2014;34:3197–203.PubMed
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Blankenstein SA, van Akkooi ACJ. Adjuvant systemic therapy in high-risk melanoma. Melanoma Res. 2019;29:358–64.CrossRef
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Metadata
Title
ASO Author Reflections: Melanoma Patients with a Local Recurrence or In-Transit Metastasis: Sentinel Node Biopsy to Identify Those at Highest Risk of Metastases and Death
Authors
Amanda A. G. Nijhuis, MD
Omgo E. Nieweg, MD
Publication date
01-02-2020
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue 2/2020
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-019-08031-1

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