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World Journal of Surgery
Published in: World Journal of Surgery 3/2020

01-03-2020 | Metastasis | Original Scientific Report

Long-Term and Oncologic Outcomes of Robotic Versus Laparoscopic Liver Resection for Metastatic Colorectal Cancer: A Multicenter, Propensity Score Matching Analysis

Authors: Rachel E. Beard, Sidrah Khan, Roberto I. Troisi, Roberto Montalti, Aude Vanlander, Yuman Fong, T. Peter Kingham, Thomas Boerner, Eren Berber, Bora Kahramangil, Joseph F. Buell, John B. Martinie, Dionisios Vrochides, Chengli Shen, Michele Molinari, David A. Geller, Allan Tsung

Published in: World Journal of Surgery | Issue 3/2020

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Abstract

Background

To assess long-term oncologic outcomes of robotic-assisted liver resection (RLR) for colorectal cancer (CRC) metastases as compared to a propensity-matched cohort of laparoscopic liver resections (LLR). Although safety and short-term outcomes of RLR have been described and previously compared to LLR, long-term and oncologic data are lacking.

Methods

A retrospective study was performed of all patients who underwent RLR and LLR for CRC metastases at six high-volume centers in the USA and Europe between 2002 and 2017. Propensity matching was used to match baseline characteristics between the two groups. Data were analyzed with a focus on postoperative and oncologic outcomes, as well as long-term recurrence and survival.

Results

RLR was performed in 115 patients, and 514 patients underwent LLR. Following propensity matching 115 patients in each cohort were compared. Perioperative outcomes including mortality, morbidity, reoperation, readmission, intensive care requirement, length-of-stay and margin status were not statistically different. Both prematching and postmatching analyses demonstrated similar overall survival (OS) and disease-free survival (DFS) between RLR and LLR at 5 years (61 vs. 60% OS, p = 0.87, and 38 vs. 31% DFS, p = 0.25, prematching; 61 vs. 60% OS, p = 0.78, and 38 vs. 44% DFS, p = 0.62, postmatching).

Conclusions

Propensity score matching with a large, multicenter database demonstrates that RLR for colorectal metastases is feasible and safe, with perioperative and long-term oncologic outcomes and survival that are largely comparable to LLR.
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Metadata
Title
Long-Term and Oncologic Outcomes of Robotic Versus Laparoscopic Liver Resection for Metastatic Colorectal Cancer: A Multicenter, Propensity Score Matching Analysis
Authors
Rachel E. Beard
Sidrah Khan
Roberto I. Troisi
Roberto Montalti
Aude Vanlander
Yuman Fong
T. Peter Kingham
Thomas Boerner
Eren Berber
Bora Kahramangil
Joseph F. Buell
John B. Martinie
Dionisios Vrochides
Chengli Shen
Michele Molinari
David A. Geller
Allan Tsung
Publication date
01-03-2020
Publisher
Springer International Publishing
Published in
World Journal of Surgery / Issue 3/2020
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-019-05270-x

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