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International Orthopaedics
Published in: International Orthopaedics 1/2021

01-01-2021 | Metastasis | Original Paper

En bloc resection and intercalary prosthesis implantation for the treatment of humeral diaphyseal bone metastases

Authors: Feifei Pu, Zhicai Zhang, Baichuan Wang, Jianxiang Liu, Zengwu Shao

Published in: International Orthopaedics | Issue 1/2021

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Abstract

Purpose

To evaluate the short-term clinical efficacy and complications of en bloc resection and intercalary prosthesis implantation for the treatment of humeral diaphyseal bone metastases.

Methods

A total of 21 patients with humeral diaphyseal bone metastases treated with en bloc resection and intercalary prosthesis implantation from August 2014 to August 2019 were retrospectively analysed. The visual analogue scale (VAS), Musculoskeletal Tumour Society (MSTS) scale, International Society of Limb Salvage (ISOLS) scoring system, Karnofsky Performance Status (KPS) scale, and Nottingham Health Profile (NHP) scale were used to assess pain, limb function, and quality of life. Survival of the patients was analysed using the Kaplan-Meier method.

Results

The patients were followed up for 12–57 months (mean: 22 months); the operative time was 68–114 minutes (mean: 76.24 min); the osteotomy length was 6.5–10 cm (mean: 8.02 cm); and the intra-operative blood loss was 95–125 ml (mean: 104.71 ml). At three, six and 12 months after surgery, the VAS and NHP scores were lower, whereas the MSTS, ISOLS, and KPS scores were higher than those before surgery, and the differences were statistically significant (P < 0.05). The survival time was four to 24 months (mean: 19.46 months). Thesix month and one year survival rates were 80.95% and 52.38%, respectively. During the follow-up period, no complications occurred except for aseptic prosthesis loosening in one patient.

Conclusions

En bloc resection and intercalary prosthesis implantation can reduce pain, improve limb function, prolong survival time, and improve quality of life in patients with humeral diaphyseal bone metastases.
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Metadata
Title
En bloc resection and intercalary prosthesis implantation for the treatment of humeral diaphyseal bone metastases
Authors
Feifei Pu
Zhicai Zhang
Baichuan Wang
Jianxiang Liu
Zengwu Shao
Publication date
01-01-2021
Publisher
Springer Berlin Heidelberg
Keyword
Metastasis
Published in
International Orthopaedics / Issue 1/2021
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-020-04845-x

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