Published in:
Open Access
01-06-2014 | Meeting abstract
Maternal tobacco use during pregnancy and risk of congenital heart defects in offspring: a systematic review
Authors:
Aspasia Tzani, Konstantinos P Economopoulos
Published in:
Tobacco Induced Diseases
|
Special Issue 1/2014
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Excerpt
Numerous human studies have investigated potential teratogenic effects of maternal smoking during pregnancy, with conflicting findings [
1,
2]. One of the most common birth malformations is congenital heart defect (CHD) with a prevalence of around 1% of live births [
3,
4]. More specifically, several studies indicate that maternal tobacco use is related with increased risk of CHD, whereas other studies do not find any association [
5,
6]. The aim of this study is to systematically review the literature regarding the correlation between maternal smoking during pregnancy and the prevalence of CHDs in offspring. …