Published in:
Open Access
01-12-2018 | Case report
Manifestation of anaplasmosis as cerebral infarction: a case report
Authors:
Seok Won Kim, Choon-Mee Kim, Dong-Min Kim, Na Ra Yun
Published in:
BMC Infectious Diseases
|
Issue 1/2018
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Abstract
Background
Human granulocytic anaplasmosis is a tick-borne zoonotic disease caused by Anaplasma phagocytophilum, an obligate intracellular granulocytotropic bacterium.
Case presentation
A 70-year-old female patient was admitted with the clinical signs of fever and an altered state of consciousness 1 week after experiencing a tick bite while planting lawn grass. Magnetic resonance imaging, performed at the time of admission, indicated cerebral infarction in the left basal ganglia, whereas increasing immunofluorescence assay antibody titers for A. phagocytophilum were also documented. A. phagocytophilum was identified using groEL and ankA targeted polymerase chain reaction and sequencing. Because of severe thrombocytopenia, only doxycycline was administered, without any antiplatelet agents. Subsequently, the symptoms improved without any focal neurologic sequela.
Conclusion
This is the first reported case of cerebral infarction occurrence in an anaplasmosis patient.