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Published in: Current Hematologic Malignancy Reports 2/2018

01-04-2018 | Stem Cell Transplantation (R Maziarz, Section Editor)

Managing the Mental Distress of the Hematopoietic Stem Cell Transplant (HSCT) Patient: a Focus on Delirium

Author: Joseph Bubalo

Published in: Current Hematologic Malignancy Reports | Issue 2/2018

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Abstract

Purpose of Review

To highlight the breadth and types of mental distress experienced by hematopoietic stem cell transplant (HSCT) patients and highlight the need for better prevention and management of delirium.

Recent Findings

Recent publications highlight additional risks factors which predict for mental distress during the HSCT process. Despite new medications and additional psychological reports, there is little progress in non-pharmacologic or medication therapy in the prevention and treatment of delirium.

Summary

Mental distress, especially delirium, is common during the HSCT process. The morbidity associated with delirium and other mental distress can still be significant at 6–12 months after the completion of the procedure affecting patient functioning and quality of life (QOL). Medication interventions may be helpful but should be used sparingly for targeted patients during HSCT. Additional interventions are needed to prevent and treat delirium in HSCT patients.
Literature
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go back to reference • LeBlanc TW. Advance care planning and palliative care specialists in malignant hematology and stem-cell transplantation: on why it takes a village. J Oncol Pract. 2017;1–3. https://doi.org/10.1200/JOP.2017.026930; published online ahead of print. Recent editorial highlighting the complexities of HSCT with insightful comments on the need for a multidisciplinary team. • LeBlanc TW. Advance care planning and palliative care specialists in malignant hematology and stem-cell transplantation: on why it takes a village. J Oncol Pract. 2017;1–3. https://​doi.​org/​10.​1200/​JOP.​2017.​026930; published online ahead of print. Recent editorial highlighting the complexities of HSCT with insightful comments on the need for a multidisciplinary team.
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go back to reference • Levy MR, Fann JR. The neuropsychiatry of hematopoietic stem cell transplantation. Eur J Psychiatry. 2006;20(2):107–28. Excellent overview of this topic if a practitioner needs a refresher or introduction. CrossRef • Levy MR, Fann JR. The neuropsychiatry of hematopoietic stem cell transplantation. Eur J Psychiatry. 2006;20(2):107–28. Excellent overview of this topic if a practitioner needs a refresher or introduction. CrossRef
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go back to reference • Teale EA, Siddiqi N, Clegg A, et al. Non-pharmacological interventions for managing delirium in hospitalized patients. Cochrane Rev Protoc. 2017;(4):CD005995, 1–9. Proposed protocol for management of HSCT patient delirium risk. Requires validation but could serve as an interim model. • Teale EA, Siddiqi N, Clegg A, et al. Non-pharmacological interventions for managing delirium in hospitalized patients. Cochrane Rev Protoc. 2017;(4):CD005995, 1–9. Proposed protocol for management of HSCT patient delirium risk. Requires validation but could serve as an interim model.
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Metadata
Title
Managing the Mental Distress of the Hematopoietic Stem Cell Transplant (HSCT) Patient: a Focus on Delirium
Author
Joseph Bubalo
Publication date
01-04-2018
Publisher
Springer US
Published in
Current Hematologic Malignancy Reports / Issue 2/2018
Print ISSN: 1558-8211
Electronic ISSN: 1558-822X
DOI
https://doi.org/10.1007/s11899-018-0441-2

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