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The Journal of Headache and Pain
Published in: The Journal of Headache and Pain 1/2015

Open Access 01-12-2016 | Research article

Management of headache and associated factors among undergraduate medicine and health science students of University of Gondar, North West Ethiopia

Authors: Eshetie Melese Birru, Zenahebezu Abay, Mohammedbrhan Abdelwuhab, Abebe Basazn, Betelhem Sirak, Fitsum Sebsibe Teni

Published in: The Journal of Headache and Pain | Issue 1/2015

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Abstract

Background

The headache disorders, namely, migraine and tension type headache and the associated analgesic consumption is badly underestimated and thus makes a major current public health problem. The objective of this study was to determine the prevalence of migraine and tension type headaches and the associated management options used among undergraduate students of College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Method

Institution based cross sectional study was conducted among 720 students in May, 2014. Pretested and structured self-administered questionnaires were used as data collecting tool followed by short interview to diagnose the type of headache based on the International Headache Society diagnostic criteria. SPSS version 20 was also used to analyse the data descriptively as well as inferentially using logistic regression models to investigate factors associated with presence of headache and analgesic use.

Result

The prevalence of lifetime headache and headache in the last 12 months was 81.11 and 67.22 %, respectively. Migraine and tension type headache were having 94 (13.06 %) and 481 (66.81 %) prevalence, respectively. Prevalence of life time headache was significant among females, students with family history of headache and lack of adequate vacation time. Similarly, lifetime prevalence of analgesic use for headache was 72.45 % and it had statistical association with sex, age, type of headache, lack of adequate vacation time and family history of headache. Majority of the students, migraineurs (54.65 %) and the tension type headache sufferers (66.17 %) commonly used paracetamol.

Conclusion

High prevalence without adequate medical care seeking behaviour and the associated significant analgesic consumption necessitate the designing of all rounded strategies to improve the quality of life of individuals with such neurologic disorders.
Literature
1.
Iliopoulos P, Damigos D, Kerezoudi E, Limpitaki G, Xifaras M, Skiada D et al (2015) Trigger factors in primary headaches subtypes: a cross-sectional study from a tertiary centre in Greece. BMC Res Notes 8:393CrossRefPubMedPubMedCentral
2.
Steiner TJ, Birbeck GL, Jensen RH, Katsarava Z, Stovner LJ, Martelletti P (2015) Headache disorders are third cause of disability worldwide. J Headache Pain 16:58CrossRefPubMedPubMedCentral
3.
Silberstein SD, Lipton RB, Goadsby PJ (2002) Headache in clinical practice. Martin Dunitz, London, 21–33, 69–128
4.
Lipton RB, Diamond S, Reed M, Diamond ML, Stewart WF (2001) Migraine diagnosis and treatment: results from the American Migraine Study II. Headache 41:638–645CrossRefPubMed
5.
Stovner LJ, Hagen K, Jensen R, Katsarava Z, Lipton R, Scher A (2007) The global burden of headache: a documentation of headache prevalence and disability worldwide. Cephalalgia 27:193–210CrossRefPubMed
6.
Silberstein SD, Lipton RB, Dalessio DJ (2001) Overview, diagnosis, and classification of headache. In: Silberstein SD, Lipton RB, Dalessio DJ (eds) Wolff’s headache and other head pain, 7th edn. Oxford University Press, New York, pp 6–26
7.
Katsarava Z, Steiner TJ (2012) Neglected headache: arrogance, ignorance or insouciance? Cephalalgia 32:1019–1020CrossRefPubMed
8.
Manandhar K, Risal A, Linde M, Steiner TJ (2016) The burden of headache disorders in Nepal: estimates from a population-based survey. J Headache Pain 17:3CrossRefPubMedCentral
9.
Ojini FI, Okubadejo NU, Danesi MA (2009) Prevalence and clinical characteristics of headache in medical students of the University of Lagos, Nigeria. Cephalalgia 29:472–477CrossRefPubMed
10.
Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M et al (2012) Years lived with disability (YLD) for 1160 sequelae of 289 diseases and injuries Steiner et al. a systematic analysis for the Global Burden of Disease Study 2010. Lancet 380:2163–2196CrossRefPubMed
11.
Rao GN, Kulkarni GB, Gururaj G, Stovner LJ, Steiner TJ (2015) The burden attributable to headache disorders in India: estimates from a community-based study in Karnataka State. J Headache Pain 16:94CrossRefPubMedPubMedCentral
12.
Lipton RB, Bigal ME (2005) The epidemiology of migraine. Am J Med 18(1):3–10
13.
Headache Classification Committee of the International Headache Society (IHS) (2013) The International Classification of Headache Disorders, 3rd Edition (beta version). Cephalalgia 33:629–808CrossRef
14.
Zebenholzer K, Andree C, Lechner A, Broessner G, Lampl C, Luthringshausen G et al (2015) Prevalence, management and burden of episodic and chronic headaches–a cross-sectional multicentre study in eight Austrian headache centres. J Headache Pain 16:46CrossRefPubMedCentral
15.
Lipton RB, Newman IC (2003) Epidemiology, impact, and comorbities of migraine headaches in the United States. Neurology 60(2):3–8
16.
Strine TW, Chapman DP, Balluz LS (2006) Population of U.S. study of severe headaches in adults: psychological distress and comorbities. Headache 46:223–232CrossRefPubMed
17.
Fendrich K, Vennemann M, Pfaffenrath V, Evers S, May A, Berger K (2007) Headache prevalence among adolescents the German DMKG headache study. Cephalalgia 27:347–354CrossRefPubMed
18.
Asdrubal FA, Alisson RO, Maíra CR, Viviane MA, Roberta CA, Thaís MA, Gustavo LI (2010) Prevalence and impact of headache in undergraduate students in Southern Brazil. Arq Neuropsiquiatr 68(6):873–877CrossRef
19.
Cevoli S, Sancisi E, Grimaldi D, Pierangeli G, Zanigni S, Nicodemo M (2009) Family history for chronic headache and drug overuse as a risk factor for headache chronification. Headache 49:412–418CrossRefPubMed
20.
Straube A, Pfaffenrath V, Ladwig K, Meisinger C, Hoffmann W, Fendrich K (2010) Prevalence of chronic migraine and medication overuse headache in Germany the German DMKG Headache Study. Cephalalgia 30:207–213CrossRefPubMed
21.
Mitsikostas DD, Gatzonis S, Thomas A, Kalfakis N, Illias A, Papageoergiou C (1996) An epidemiological study of headaches among medical students in Athens. Headache 36:561–564CrossRefPubMed
22.
Mehuys E, Paemeleire K, Hees TV, Christiaens T, Van Bortel LM, Van Tongelen I et al (2012) Self-medication of regular headache: a community pharmacy-based survey. Eur J Neurol 19:1093–1099CrossRefPubMed
23.
Demirkirkan MK, Ellidokuz H, Boluk A (2006) Prevalence and clinical characteristics of migraine in university students in Turkey. Tohoku J Exp Med 208:87–92CrossRefPubMed
24.
Ruchika NA, Mahinder KC (2013) Prevalence and clinical characteristics of headache in dental students of a tertiary care teaching dental hospital in Northern India. IJBCP 2(1):51–55
25.
Samuelsen P, Slørdal L, Mathisen UD, Eggen AE (2015) Analgesic use in a Norwegian general population: change over time and high-risk use. BMC Pharmacol Toxicol 16:16CrossRefPubMedPubMedCentral
26.
Saedder E, Brock B, Nielsen L, Bonnerup D, Lisby M (2014) Identifying high-risk medication: a systematic literature review. Eur J Clin Pharmacol 70(6):637–645CrossRefPubMed
27.
Mengistu G, Alemayehu S (2013) Prevalence and burden of primary headache disorders among a local community in Addis Ababa, Ethiopia. J Headache Pain 14:30CrossRefPubMedPubMedCentral
28.
Ho KH, Ong BK (2003) Community-based study of headache diagnosis and prevalence in Singapore. Cephalalgia 23:6–13CrossRefPubMed
29.
Falavigna A, Teles AR, Velho MC, Vedana VM, Silva RC, Mazzocchin T et al (2010) Prevalence and impact of headache in undergraduate students in Southern Brazil. Arq Neuropsiquiatr 68(6):873–877CrossRefPubMed
30.
Ferri-de-Barros JE, Alencar MJ, Berchielli LF, Junior LCC (2011) Headache among medical and psychology students. Arq Neuropsiquiatr 69(3):502–508CrossRefPubMed
31.
Barae LM, Rotta NT, Stein A, Barros HMT, Tannhausser M (1997) Analgesic use for headache treatment by schoolchildren of southern Brazil. Pharmacoepidemiol Drug Saf 6(5):359–366CrossRef
32.
Onwuekwe I, Onyeka T, Aguwa E, Ezeala-Adikaibe B, Ekenze O, Onuora E (2014) Headache prevalence and its characterization amongst hospital workers in Enugu, South East Nigeria. Head Face Med 10:48CrossRefPubMedPubMedCentral
33.
Domingues RB, Aquino CH, Santos JG, Pirajá da Silva AL, Kuster GH (2006) Prevalence and impact of headache and migraine among Pomeranians in Espirito Santo, Brazil. Arq Neuropsiquiatr 64(4):954–957CrossRefPubMed
34.
Pagel MD, Erdly WW, Becker J (1987) Social networks: we get by with (and in spite of) a little help from our friends. J Pers Soc Psychol 53:793–804CrossRefPubMed
35.
Wang Y, Xie J, Yang F, Wu S, Wang H, Zhang X, Liu H, Deng X, Yu S (2015) The prevalence of primary headache disorders and their associated factors among nursing staff in North China. J Headache Pain 16:4CrossRefPubMedPubMedCentral
36.
Straube A, Heinen F, Ebinger F, Kries R (2013) Headache in school children: prevalence and risk factors. Dtsch Arztebl Int 110(48):811–818PubMedPubMedCentral
37.
Rainero I, Rubino E, Paemeleire K, Gai A, Vacca A, Martino P et al (2013) Genes and primary headaches: discovering new potential therapeutic targets. J Headache Pain 14:61CrossRefPubMedPubMedCentral
38.
Anttila V, Stefansson H, Kallela M, Todt U, Terwindt GM, Calafato MS et al (2010) Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1. Nat Genet 42:869–873CrossRefPubMedPubMedCentral
39.
Chasman DI, Schürks M, Anttila V, de Vries B, Schminke U, Launer LJ et al (2011) Genome-wide association study reveals three susceptibility loci for common migraine in the general population. Nat Genet 43:695–698CrossRefPubMedPubMedCentral
40.
Teklehymanot R, Seraw B, Forsgen L, Ekbom K, Ekstedt J (2002) Migraine, chronic tension type and cluster headache in Ethiopian rural community. Cephalelgia 15(6):482–488
41.
42.
Adoukonou T, Tognon-Tchegnonsi F, Philomène K, Alabi A, Dismand Houinato D, Preux P (2014) Prevalence of migraine among university students at Parakou, Benin: a cross-sectional study. World J Neurosci 4:18–24CrossRef
43.
Woldeamanuel YW, Andreou AP, Cowan RP (2014) Prevalence of migraine headache and its weight on neurological burden in Africa: a 43-year systematic review and meta-analysis of community-based studies. J Neurol Sci 342(1–2):1–15CrossRefPubMed
44.
Baykan B, Ertas M, Karlı N, Uluduz D, Uygunoglu U, Ekizoglu E et al (2015) Migraine incidence in 5 years: a population-based prospective longitudinal study in Turkey. J Headache Pain 16:103CrossRefPubMedPubMedCentral
45.
Demirkirkan MK, Ellidokuz H, Boluk A (2006) Prevalence and clinical characterstics of migraine in University students in Turkey. Tohoku J Exp Med 208:87–92CrossRefPubMed
46.
Zivadino R, Willheim K, Sepic-Grahovac D, Jurjevic A, Bucuk M, Brnabic-Razmilic O et al (2003) Migraine and tension type headache in Croatia. A population based survey of precipitating factors. Cepahalelgia 23(5):336–343CrossRef
47.
Nikiforow R, Hokkanen E (1998) An epidemiological study of headache in an urban and rural population in Northern Finland. Headache 18:137–145CrossRef
48.
Levy D, Strassman AM, Burstein R (2009) A critical view on the role of migraine triggers in the genesis of migraine pain. Headache 49:953–957CrossRefPubMed
49.
50.
Heinsick LM (1996) The use and abuse of medication for the immediate relief of headache. UFSC, Santa Catarina, Brazil
51.
Sanvito WL, Monzillo PH, Prieto Peres MF, Martinelli MO, Fera MP, Gouveia DC et al (1996) The epidemiology of migraine in medical students. Headache 36:316–319CrossRefPubMed
52.
Gouvêa Da Costa MZ, Soares CB, Heinisch LM, Heinisch RH (2000) Frequency of headache in medical students, Santa Catarina’s Federal University. Headache 40:740–744CrossRef
53.
Rocha-Filho PAS, Santos PV (2014) Headaches, quality of life, and academic performance in schoolchildren and adolescents. Headache 54(7):1194–1202CrossRefPubMed
54.
Timothy SY, Mava Y, Bashir HJ, Bwala AY (2012) Impact of acute migraine headache amongst university students in North-Eastern Nigeria. IRJP 3(4):134–136
55.
56.
Antonov K, Isacson D. Headache and analgesic use in Sweden. J headache pain. 1998;38(2):97–104.CrossRef
57.
Oliveira de Almeida CM, Machado da Silva Lima PA, Stabenow R, Sylvia de Souza Mota R, Boechat A, Takatani M. Headache-related disability among medical students in Amazon: a cross-sectional study. Arq Neuropsiquiatr. 2015;73(12):1009–1013.
58.
Smitherman TA, Burch R, Sheikh H, Loder E (2013) The prevalence, impact, and treatment of migraine and severe headaches in the United States: a review of statistics from national surveillance studies. Headache 53:427–436CrossRefPubMed
59.
Pringsheim T, Davenport WJ, Mackie G, Worthington I, Aubé M, Christie SN, Gladstone J, Becker WJ (2012) Canadian headache society guideline for migraine prophylaxis. Can J Neurol Sci 39(2):1–60
60.
Paemeleire EMK, Van Hees T, Christiaens T, Van Bortel LM, Tongelen I, De Bolle L et al (2012) Self-medication of regular headache: a community pharmacy-based survey. Eur J Neurol 19(8):1093–1099CrossRefPubMed
61.
Ray WA, Schaffner W, Fraderspid CF (1986) Difference between male and female children in the receipt of prescribed and controlled analgesic drugs. Med Care 24:801–818CrossRefPubMed
62.
63.
Van tyle WK (1996) Internal analgesic products. In: Hand book of non-prescription drugs, 8th edn. American Pharmaceutical Association, Washington DC, pp 191–205
64.
Dyb G, Holmen JA, Zwart JA (2006) Analgesic over use among adolescents with headache. The head hunt-youth study. Neurology 66(2):198–201CrossRefPubMed
Metadata
Title
Management of headache and associated factors among undergraduate medicine and health science students of University of Gondar, North West Ethiopia
Authors
Eshetie Melese Birru
Zenahebezu Abay
Mohammedbrhan Abdelwuhab
Abebe Basazn
Betelhem Sirak
Fitsum Sebsibe Teni
Publication date
01-12-2016
Publisher
Springer Milan
Published in
The Journal of Headache and Pain / Issue 1/2015
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI
https://doi.org/10.1186/s10194-016-0647-4

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