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Diagnostic Pathology
Published in: Diagnostic Pathology 1/2012

Open Access 01-12-2012 | Case Report

Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report

Authors: Maddalena Borriello, Alessandro Lucidi, Arnaldo Carbone, Vito Iannone, Gabriella Ferrandina

Published in: Diagnostic Pathology | Issue 1/2012

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Abstract

Abstract

Madelung’s disease or multiple symmetric lipomatosis (MSL) is a rare disorder of unknown etiology which typically presents symmetrically subcutaneous accumulation of non-encapsulated adipose tissue which slowly grows around the neck, upper part of the arms, pelvis, back and thigh. This disease is also frequently associated with hepatopathy, glucose intolerance, hyperuricemia, and malignant tumors of the upper airways. Nevertheless, only one description of malignant transformation of Madelung’s disease has been presented in literature. Here, we report a case of liposarcomatous transformation of Madelung’s disease in a 59-year-old Italian woman with a coincidental diagnosis of breast cancer.

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Literature
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Metadata
Title
Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report
Authors
Maddalena Borriello
Alessandro Lucidi
Arnaldo Carbone
Vito Iannone
Gabriella Ferrandina
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Diagnostic Pathology / Issue 1/2012
Electronic ISSN: 1746-1596
DOI
https://doi.org/10.1186/1746-1596-7-116

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