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Malaria Journal
Published in: Malaria Journal 1/2013

Open Access 01-12-2013 | Review

Malaria in South America: a drug discovery perspective

Authors: Luiza R Cruz, Thomas Spangenberg, Marcus VG Lacerda, Timothy NC Wells

Published in: Malaria Journal | Issue 1/2013

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Abstract

The challenge of controlling and eventually eradicating malaria means that new tools are urgently needed. South America’s role in this fight spans both ends of the research and development spectrum: both as a continent capable of discovering and developing new medicines, and also as a continent with significant numbers of malaria patients. This article reviews the contribution of groups in the South American continent to the research and development of new medicines over the last decade. Therefore, the current situation of research targeting malaria control and eradication is discussed, including endemicity, geographical distribution, treatment, drug-resistance and diagnosis. This sets the scene for a review of efforts within South America to discover and optimize compounds with anti-malarial activity.
Appendix
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Metadata
Title
Malaria in South America: a drug discovery perspective
Authors
Luiza R Cruz
Thomas Spangenberg
Marcus VG Lacerda
Timothy NC Wells
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Malaria Journal / Issue 1/2013
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/1475-2875-12-168

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