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BMC Neurology
Published in: BMC Neurology 1/2021

Open Access 01-12-2021 | Magnetoencephalography | Case report

Using EEG and MEG to characterize extreme delta brush in a patient with anti-NMDA receptor encephalitis

Authors: Ailiang Miao, Yongwei Shi, Jing Xiang, Xiaoshan Wang, Jianqing Ge, Qiqi Chen, Yuanwen Yu, Chuanyong Yu, Di Wu

Published in: BMC Neurology | Issue 1/2021

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Abstract

Background

Extreme delta brush (EDB) is considered a potential marker for anti-N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis. The brain regions involved in EDB are unclear.

Case presentation

A 16-year-old woman with anti-NMDAR encephalitis who was experiencing psychosis was admitted. Electroencephalography (EEG) and magnetoencephalography (MEG) were used to analyze EDB in the patient. EDB on EEG could be disturbed by opening and closing the eyes, by occipital alpha rhythms and by sleep-wake cycles. The MEG results showed beta activity originating from bilateral superior parietal lobes. However, the delta wave originated from bilateral superior temporal gyri, the right middle temporal gyrus, the right inferior frontal gyrus, and the left inferior parietal lobe.

Conclusions

Delta wave and beta activity might originate from different brain regions. Beta activity might be transmitted forward to the frontotemporal lobe and superimposed with delta activity to form EDB on EEG.
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Metadata
Title
Using EEG and MEG to characterize extreme delta brush in a patient with anti-NMDA receptor encephalitis
Authors
Ailiang Miao
Yongwei Shi
Jing Xiang
Xiaoshan Wang
Jianqing Ge
Qiqi Chen
Yuanwen Yu
Chuanyong Yu
Di Wu
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2021
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/s12883-021-02157-0

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