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08-09-2022 | Magnetic Resonance Imaging | Editorial Comment

Towards a judicious use of perilesional biopsy in the era of MRI-targeting, parting of the ways from systematic prostate biopsy

Authors: Anwar R. Padhani, Steven S. Raman, Ivo G. Schoots

Published in: European Radiology | Issue 11/2022

Excerpt

There are many reasons why MRI-targeted biopsies (MRTB) in men with positive MRI scans fail to detect high-grade cancers that are found incidentally by concurrent systemic biopsies. Multiple factors often acting together contribute to the missed diagnoses of ISUP GG ≥ 2 cancers and/or tumour under grading [1]. The most obvious cause is an MRI invisible lesion on a background of transition zone hyperplasia, peripheral zone scarring/inflammation, or in difficult to evaluate regions such as adjacency to the ejaculatory ducts, central zone, bladder, low apex, or the anterior fibromuscular stroma. Some histologic subtypes of GG ≥ 2 prostate cancers are also difficult to see such as non-mass forming (microfocal) GG2 cancers and small cribriform tumours. Inevitably, radiologic perception errors also contribute, related to image quality, observer experience and variability, and misclassifications errors. …

Williams C, Ahdoot M, Daneshvar MA et al (2022) Why does magnetic resonance imaging-targeted biopsy miss clinically significant cancer? J Urol 207:95–107. https://doi.org/10.1097/JU.0000000000002182CrossRef

Stavrinides V, Syer T, Hu Y et al (2021) False positive multiparametric magnetic resonance imaging phenotypes in the biopsy-naïve prostate: are they distinct from significant cancer-associated lesions? Lessons from PROMIS. Eur Urol 79:20–29. https://doi.org/10.1016/j.eururo.2020.09.043

Vickers AJ (2021) Effects of magnetic resonance imaging targeting on overdiagnosis and overtreatment of prostate cancer. Eur Urol 80:567–572. https://doi.org/10.1016/j.eururo.2021.06.026CrossRef

Mottet N, Cornford P, Van Den Bergh RCN (2022) EAU - EANM - ESTRO - ESUR - ISUP - SIOG guidelines on prostate cancer. EAU Guidel Edn Present EAU Annu Congr Amsterdam 2022 ISBN 978-94-92671-16-5

Deniffel D, Perlis N, Ghai S et al (2022) Prostate biopsy in the era of MRI-targeting: towards a judicious use of additional systematic biopsy. Eur Radiol. https://doi.org/10.1007/s00330-022-08822-3

Ahdoot M, Lebastchi AH, Long L et al (2021) Using Prostate Imaging-Reporting and Data System (PI-RADS) scores to select an optimal prostate biopsy method: a secondary analysis of the TRIO study. Eur Urol Oncol 24:1110–1119. https://doi.org/10.1016/j.euo.2021.03.004CrossRef

Padhani AR, Barentsz J, Villeirs G et al (2019) PI-RADS Steering Committee: the PI-RADS multiparametric MRI and MRI-directed biopsy pathway. Radiology 292:464–474. https://doi.org/10.1148/radiol.2019182946CrossRef

Hagens MJ, Fernandez Salamanca M, Padhani AR et al (2022) Diagnostic performance of a magnetic resonance imaging-directed targeted plus regional biopsy approach in prostate cancer diagnosis: a systematic review and meta-analysis. Eur Urol Open Sci 40:95–103. https://doi.org/10.1016/j.euros.2022.04.001

Raman AG, Sarma KV, Raman SS et al (2021) Optimizing spatial biopsy sampling for the detection of prostate cancer. J Urol 206:595–603. https://doi.org/10.1097/JU.0000000000001832CrossRef

10.

Brisbane WG, Priester AM, Ballon J et al (2022) Targeted prostate biopsy: umbra, penumbra, and value of perilesional sampling. Eur Urol 1–8. https://doi.org/10.1016/j.eururo.2022.01.008

11.

Iczkowski KA, van Leenders GJLH, van der Kwast TH (2021) The 2019 International Society of Urological Pathology (ISUP) Consensus Conference on Grading of Prostatic Carcinoma. Am J Surg Pathol 45:1007. https://doi.org/10.1097/PAS.0000000000001678CrossRef

12.

Simsir A, Kismali E, Mammadov R et al (2010) Is it possible to predict sepsis, the most serious complication in prostate biopsy? Urol Int 84:395–399. https://doi.org/10.1159/000296290CrossRef

Title: Towards a judicious use of perilesional biopsy in the era of MRI-targeting, parting of the ways from systematic prostate biopsy
Authors: Anwar R. Padhani
Steven S. Raman
Ivo G. Schoots
Publication date: 08-09-2022
Publisher: Springer Berlin Heidelberg
Keywords: Magnetic Resonance Imaging
Magnetic Resonance Imaging
Published in: European Radiology / Issue 11/2022
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-022-09097-4

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Towards a judicious use of perilesional biopsy in the era of MRI-targeting, parting of the ways from systematic prostate biopsy

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