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Japanese Journal of Radiology

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01-09-2019 | Magnetic Resonance Imaging | Technical Note

The opacity of mineral ion-loaded bead (DC beads^®) on low-keV monochromatic images from dual energy CT and T1-weighted gradient-echo MRI

Authors: Keizo Tanitame, Nobuko Tanitame, Yuji Takahashi, Erika Tamai, Taichi Kurose

Published in: Japanese Journal of Radiology | Issue 9/2019

Abstract

Purpose

To evaluate the opacity of DC beads^® (DCB) loaded with mineral ions on low-keV monochromatic images from dual energy computed tomography (DECT) and T1-weighted gradient-echo (T1-GRE) MRI.

Materials and methods

Fe²⁺ or Ca²⁺-loaded DCBs were prepared by mixing DCBs in 100 mM FeSO₄ or CaSO₄ solution and scanned by DECT from 10 min to 27 h after mixing. The Hounsfield units (HUs) of sedimented DCBs on 40-keV monochromatic images were measured. Next, we mixed DCBs in 100, 10, 5 and 1 mM FeSO₄ solutions, and scanned these solutions from 15 to 120 min after mixing using a 3 T MR scanner. The signal–noise ratios (SNRs) of sedimented DCBs on T1-GRE were measured. Venous blood was scanned to compare with DCBs.

Results

The CT values of DCBs in FeSO₄ and CaCl₂ solutions gradually increased, and were 113.3 and 43.1 HU at 27 h, respectively; that of blood was 17.8 HU. The SNR of DCB in 1 mM FeSO₄ solution increased and achieved equilibrium at 120 min, and was 120.5 and higher than in the other FeSO₄ solutions. The SNR of blood was 49.7.

Conclusion

Optimally Fe²⁺-loaded DCBs can be discriminated from venous blood on 40-keV monochromatic images from DECT and T1-GRE.

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Title: The opacity of mineral ion-loaded bead (DC beads®) on low-keV monochromatic images from dual energy CT and T1-weighted gradient-echo MRI
Authors: Keizo Tanitame
Nobuko Tanitame
Yuji Takahashi
Erika Tamai
Taichi Kurose
Publication date: 01-09-2019
Publisher: Springer Japan
Keywords: Magnetic Resonance Imaging
Magnetic Resonance Imaging
Computed Tomography
Computed Tomography
Published in: Japanese Journal of Radiology / Issue 9/2019
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI: https://doi.org/10.1007/s11604-019-00856-w

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The opacity of mineral ion-loaded bead (DC beads^®) on low-keV monochromatic images from dual energy CT and T1-weighted gradient-echo MRI

Abstract

Purpose

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Materials and methods

Results

Conclusion

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