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Published in: Neurological Sciences 4/2022

01-04-2022 | Magnetic Resonance Imaging | Review Article

Neurological side effects of radiation therapy

Authors: J. Jacob, L. Feuvret, J.-M. Simon, M. Ribeiro, L. Nichelli, C. Jenny, D. Ricard, D. Psimaras, K. Hoang-Xuan, P. Maingon

Published in: Neurological Sciences | Issue 4/2022

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Abstract

Radiation therapy (RT) is one of the main treatments administered to patients with cancer. The development of technology has improved RT accuracy by allowing more precise delivery of high doses to the target volumes with reduced exposure of healthy tissue. Life expectancy has increased due to these therapeutic advancements and the patients’ quality of life remains a major concern. The adverse events related to RT are quite various and most likely will impair essential neurological functions, e.g. cognitive status. This literature review aims to describe the physiopathological processes, the neurological symptoms as well as the local modifications observed in magnetic resonance imaging following RT. The specific therapeutic options and preventive actions will also be discussed.
Literature
9.
go back to reference Li YQ, Chen P, Haimovitz-Friedman A et al (2003) Endothelial apoptosis initiates acute blood-brain barrier disruption after ionizing radiation. Cancer Res 63:5950–5956PubMed Li YQ, Chen P, Haimovitz-Friedman A et al (2003) Endothelial apoptosis initiates acute blood-brain barrier disruption after ionizing radiation. Cancer Res 63:5950–5956PubMed
50.
go back to reference Chi D, Behin A, Delattre J-Y (2008) Neurologic complications of radiation therapy. In: Schiff D, Kesari S, Wen PY (eds) Cancer Neurology in Clinical Practice. Humana Press, New Jersey, pp 259–286CrossRef Chi D, Behin A, Delattre J-Y (2008) Neurologic complications of radiation therapy. In: Schiff D, Kesari S, Wen PY (eds) Cancer Neurology in Clinical Practice. Humana Press, New Jersey, pp 259–286CrossRef
Metadata
Title
Neurological side effects of radiation therapy
Authors
J. Jacob
L. Feuvret
J.-M. Simon
M. Ribeiro
L. Nichelli
C. Jenny
D. Ricard
D. Psimaras
K. Hoang-Xuan
P. Maingon
Publication date
01-04-2022
Publisher
Springer International Publishing
Published in
Neurological Sciences / Issue 4/2022
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-022-05944-w

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