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European Radiology

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Open Access 01-05-2021 | Magnetic Resonance Imaging | Breast

MRI-guided breast biopsy based on diffusion-weighted imaging: a feasibility study

Authors: Stefania Montemezzi, Giuseppe Cardano, Silvia Storer, Nicolò Cardobi, Carlo Cavedon, Lucia Camera

Published in: European Radiology | Issue 5/2021

Abstract

Objectives

This study evaluated the feasibility of DWI for lesion targeting in MRI-guided breast biopsies. Furthermore, it assessed device positioning on DWI during biopsy procedures.

Methods

A total of 87 biopsy procedures (5/87 bilateral) consecutively performed between March 2019 and June 2020 were retrospectively reviewed: in these procedures, a preliminary DWI sequence (b = 1300 s/mm²) was acquired to assess lesion detectability. We included 64/87 procedures on lesions detectable at DWI; DWI sequences were added to the standard protocol to localize lesion and biopsy device and to assess the site marker correct positioning.

Results

Mass lesions ranged from 5 to 48 mm, with a mean size of 10.7 mm and a median size of 8 mm. Non-mass lesions ranged from 7 to 90 mm, with a mean size of 33.9 mm and a median size of 31 mm. Positioning of the coaxial system was confirmed on both T1-weighted and DWI sequences. At DWI, the biopsy needle was detectable in 62/64 (96.9%) cases; it was not visible in 2/64 (3.1%) cases. The site marker was always identified using T1-weighted imaging; a final DWI sequence was acquired in 44/64 cases (68.8%). In 42/44 cases (95.5%), the marker was recognizable at DWI.

Conclusions

DWI can be used as a cost-effective, highly reliable technique for targeting both mass and non-mass lesions, with a minimum size of 5 mm, detectable at pre-procedural DWI. DWI is also a feasible technique to localize the biopsy device and to confirm the deployment of the site marker.

Key Points

• MRI-guided breast biopsy is performed in referral centers by an expert dedicated staff, based on prior MR imaging; contrast agent administration is usually needed for lesion targeting.

• DWI represents a feasible, highly reliable technique for lesion targeting, avoiding contrast agent administration.

• DWI allows a precise localization of both biopsy needle device and site marker.

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Title: MRI-guided breast biopsy based on diffusion-weighted imaging: a feasibility study
Authors: Stefania Montemezzi
Giuseppe Cardano
Silvia Storer
Nicolò Cardobi
Carlo Cavedon
Lucia Camera
Publication date: 01-05-2021
Publisher: Springer Berlin Heidelberg
Keywords: Magnetic Resonance Imaging
Magnetic Resonance Imaging
Published in: European Radiology / Issue 5/2021
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-020-07396-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

MRI-guided breast biopsy based on diffusion-weighted imaging: a feasibility study

Abstract

Objectives

Methods

Results

Conclusions

Key Points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

Key Points

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