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European Radiology

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01-07-2010 | Breast

Vacuum-assisted biopsies under MR guidance: results of 72 procedures

Authors: C. Malhaire, C. El Khoury, F. Thibault, A. Athanasiou, P. Petrow, L. Ollivier, A. Tardivon

Published in: European Radiology | Issue 7/2010

Abstract

Objective

To investigate the clinical accuracy of magnetic resonance imaging-guided breast vacuum-assisted biopsy (MR-VAB).

Methods

Of 97 scheduled MR-VAB for single MRI lesions (negative second-look sonography) categorised as BI-RADS 4 or 5, 4 were cancelled (undetected lesion = 2, technical problems = 2). Twenty-one patients lost to follow-up were excluded.

Results

Twenty-three patients (median age 51 years) were at high risk (BRCA1 = 11, BRCA2 = 7, familial risk = 5), 23 had a suspected local recurrence of breast cancer. Seventy-two imaged lesions (focus = 1, mass enhancement = 32, non-mass-like enhancement = 39) were targeted with a 10-gauge VAB probe using MRI guidance, with a median of 18 specimens per lesion (median procedural time 72 min, range 50–131 min) followed by clip placement. In the case of benignity, MRI follow-up was performed (19 patients, median 389 days, range 33–1,592) or mammography (3 patients, median 420 days, range 372–1,354). According to histopathology results, 29 lesions were benign, 10 were high-risk (papillary = 2, radial scar = 1, atypical epithelial hyperplasia = 7) and 33 malignant (ductal carcinoma in situ = 8, invasive cancers = 25). Three false negative results and 3 complications occurred (1 malaise, 1 skin defect, 1 infection).

Conclusion

MRI-guided VAB represents an accurate tool for the histological diagnosis of lesions visible only at MRI.

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Title: Vacuum-assisted biopsies under MR guidance: results of 72 procedures
Authors: C. Malhaire
C. El Khoury
F. Thibault
A. Athanasiou
P. Petrow
L. Ollivier
A. Tardivon
Publication date: 01-07-2010
Publisher: Springer-Verlag
Published in: European Radiology / Issue 7/2010
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-009-1707-9

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Vacuum-assisted biopsies under MR guidance: results of 72 procedures

Abstract

Objective

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Objective

Methods

Results

Conclusion

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