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01-12-2021 | Magnetic Resonance Imaging | Original Article

Impact of paravertebral muscle in thoracolumbar and lower lumbar regions on outcomes following osteoporotic vertebral fracture: a multicenter cohort study

Authors: Hasibullah Habibi, Shinji Takahashi, Masatoshi Hoshino, Kazushi Takayama, Ryuichi Sasaoka, Tadao Tsujio, Hiroyuki Yasuda, Fumiaki Kanematsu, Hiroshi Kono, Hiromitsu Toyoda, Shoichiro Ohyama, Yusuke Hori, Hiroaki Nakamura

Published in: Archives of Osteoporosis | Issue 1/2021

Abstract

Summary

We investigated the effect of paravertebral muscle (PVM) on poor prognosis in osteoporotic vertebral fracture (OVF) and remaining lower back pain (LBP) in the thoracolumbar and lower lumbar regions. Additional OVF occurrence in the thoracolumbar and remaining LBP in the lumbar region was significantly related to PVM fat infiltration percentage.

Purpose

Paravertebral muscle (PVM) is an important component of the spinal column. However, its role in the healing process after osteoporotic vertebral fracture (OVF) is unclear. This study aimed to clarify the effect of PVM in thoracolumbar and lower lumbar regions on OVF clinical and radiological outcomes.

Methods

This was a multicenter prospective cohort study from 2012 to 2015. Patients ≥ 65 years old who presented within 2 weeks after fracture onset were followed up for 6 months. PVM was measured at the upper edge of the L1 and L5 vertebral body in the magnetic resonance imaging (MRI) T2-axial position at registration. The cross-sectional area (CSA), relative CSA (rCSA), and fat infiltration percentage (FI%) were measured. Severe vertebral compression, delayed union, new OVF, and remaining low back pain (LBP) were analyzed.

Results

Among 153 patients who were followed up for 6 months, 117 with measurable PVM were analyzed. Their average age was 79.1 ± 7.2 years, and 94 were women (80.3%). There were 48 cases of severe vertebral compression, 21 delayed unions, 11 new OVF, and 27 remaining LBP. Among all poor prognoses, only the FI% of the PVM was significantly associated with new OVF (p = 0.047) in the thoracolumbar region and remaining LBP (p = 0.042) in the lumbar region.

Conclusion

The occurrence of additional OVF in the thoracolumbar region and remaining LBP in the lumbar region was significantly related to the FI% of the PVM. Physicians should be aware that patients with such fatty degeneration shown in acute MRI may require stronger treatment.

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Title: Impact of paravertebral muscle in thoracolumbar and lower lumbar regions on outcomes following osteoporotic vertebral fracture: a multicenter cohort study
Authors: Hasibullah Habibi
Shinji Takahashi
Masatoshi Hoshino
Kazushi Takayama
Ryuichi Sasaoka
Tadao Tsujio
Hiroyuki Yasuda
Fumiaki Kanematsu
Hiroshi Kono
Hiromitsu Toyoda
Shoichiro Ohyama
Yusuke Hori
Hiroaki Nakamura
Publication date: 01-12-2021
Publisher: Springer London
Keywords: Magnetic Resonance Imaging
Magnetic Resonance Imaging
Back Pain
Back Pain
Back Pain
Published in: Archives of Osteoporosis / Issue 1/2021
Print ISSN: 1862-3522
Electronic ISSN: 1862-3514
DOI: https://doi.org/10.1007/s11657-020-00866-6

At a glance: The STEP trials

Springer Medicine

Impact of paravertebral muscle in thoracolumbar and lower lumbar regions on outcomes following osteoporotic vertebral fracture: a multicenter cohort study

Abstract

Summary

Purpose

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Summary

Purpose

Methods

Results

Conclusion

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