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Neurocritical Care
Published in: Neurocritical Care 2/2022

12-07-2022 | Magnetic Resonance Imaging | Neuroimage

Expansion of Hemorrhage in Critical Herpes Simplex Encephalitis

Authors: Monica Krause, Sherri Braksick, Eelco Wijdicks

Published in: Neurocritical Care | Issue 2/2022

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Excerpt

Herpes simplex virus (HSV) is a common cause of viral encephalitis, often presenting with insidious, nonspecific onset [1]. Focal examination findings may include hemiparesis, spatial neglect, aphasia, or hemianopia [1]. On computed tomography (CT) scans, the mesial temporal lobe is most frequently affected [2]. Magnetic resonance imaging (MRI) often shows more abnormalities in the insular cortex, bilateral limbic system, and petechial hemorrhages within the cortex and subcortical white matter [3]. …
Literature
1.
Bulakbasi N, Kocaoglu M. Central nervous system infections of herpesvirus family. Neuroimaging Clin N Am. 2008;18:53–84.CrossRef
2.
Byun YH, Ha EJ, Ko S-B, Kim KH. Decompressive craniectomy for herpes simplex encephalitis complicated by frank intracerebral hemorrhage: a case report and review of the literature. BMC Neurol. 2018;18:176.CrossRef
3.
Veiga Canuto D, Carreres Polo J, Aparici Robles F, Quiroz TA. Acute cerebral haematoma in the course of herpes simplex encephalitis: a rare complication. Neurología (English Edition). 2021;36:80–2.CrossRef
4.
Sivasankar C, Ayodele M. Herpes simplex virus (HSV) encephalitis presenting as spontaneous intracerebral hemorrhage (ICH) (P5.050). Neurology. 2017;88:P5.050.
5.
Sarton B, Jaquet P, Belkacemi D, de Montmollin E, Bonneville F, Sazio C, et al. Assessment of magnetic resonance imaging changes and functional outcomes among adults with severe herpes simplex encephalitis. JAMA Netw Open. 2021;4: e2114328.CrossRef
6.
Hauer L, Pikija S, Schulte EC, Sztriha LK, Nardone R, Sellner J. Cerebrovascular manifestations of herpes simplex virus infection of the central nervous system: a systematic review. J Neuroinflammation. 2019;16:19.CrossRef
7.
ElShimy G, Mariyam Joy C, Berlin F, Lashin W. Intracranial hemorrhage complicating herpes simplex encephalitis on antiviral therapy: a case report and review of the literature. Case Rep Infect Dis. 2017;2017:6038146.PubMedPubMedCentral
8.
Mak G, Lu J-Q, de Sa BD, Perera K. Herpes simplex virus type 2 encephalitis presenting as multifocal hemorrhagic stroke. Can J Neurol Sci. 2020;47:563–5.CrossRef
9.
Erdem G, Vanderford PA, Bart RD. Intracranial hemorrhage in herpes simplex encephalitis: an unusual presentation. Pediatr Neurol. 2002;27:221–3.CrossRef
10.
Biswas A, Das SK, Roy T, Dhibar T, Ghorai SP. Acute intracerebral haematoma—an unusual presentation of herpes simplex encephalitis. J Assoc Physicians India. 2004;52:69–71.PubMed
11.
Mahale RR, Mehta A, Shankar AK, Miryala A, Acharya P, Srinivasa R. Bilateral cerebral hemorrhage in herpes simplex encephalitis: rare occurrence. J Neurosci Rural Pract. 2016;7:S128–30.CrossRef
12.
Kabakus N, Gurgoze MK, Yildirim H, Godekmerdan A, Aydin M. Acute hemorrhagic leukoencephalitis manifesting as intracerebral hemorrhage associated with herpes simplex virus type I. J Trop Pediatr. 2005;51:245–9.CrossRef
13.
Fisahn C, Tkachenko L, Moisi M, Rostad S, Umeh R, Zwillman ME, et al. Herpes simplex encephalitis of the parietal lobe: a rare presentation. Cureus. 2016;8: e785.PubMedPubMedCentral
14.
Mueller K, Ryan JE, Tai A, Armonda RA. Delayed temporal lobe hemorrhage after initiation of acyclovir in an immunocompetent patient with herpes simplex virus-2 encephalitis: a case report. Cureus. 2017;9: e980.PubMedPubMedCentral
15.
Counsell CE, Taylor R, Whittle IR. Focal necrotising herpes simplex encephalitis: a report of two cases with good clinical and neuropsychological outcomes. J Neurol Neurosurg Psychiatry. 1994;57:1115–7.CrossRef
16.
Lo WB, Wilcock DJ, Carey M, Albanese E. Neurological picture. Herpes encephalitis complicated by cerebral hemorrhage. J Neurol Neurosurg Psychiatry. 2013;84:1404–6.CrossRef
17.
Jabbour PM, Ojemann SG. Herpes simplex encephalitis. Is anticoagulation safe? Neurologist. 2005;11:187–9.CrossRef
18.
Yan HJ. Herpes simplex encephalitis: the role of surgical decompression. Surg Neurol. 2002;57:20–4.CrossRef
19.
Li JZ, Sax PE. HSV-1 encephalitis complicated by cerebral hemorrhage in an HIV-positive person. AIDS Read. 2009;19:153–5.PubMed
20.
Rodríguez-Sainz A, Escalza-Cortina I, Guio-Carrión L, Matute-Nieves A, Gómez-Beldarrin M, Carbayo-Lozano G, et al. Intracerebral hematoma complicating herpes simplex encephalitis. Clin Neurol Neurosurg. 2013;115:2041–5.CrossRef
21.
Fukushima Y, Tsuchimochi H, Hashimoto M, Yubi T, Nakajima Y, Fukushima T, et al. [A case of herpetic meningoencephalitis associated with massive intracerebral hemorrhage during acyclovir treatment: a rare complication]. No Shinkei Geka. 2010;38:171–6.PubMed
22.
Battaglia F, Noudel R, Roche PH. Herpes simplex virus encephalitis requiring emergency surgery. Rev Neurol (Paris). 2013;169:182–3.CrossRef
Metadata
Title
Expansion of Hemorrhage in Critical Herpes Simplex Encephalitis
Authors
Monica Krause
Sherri Braksick
Eelco Wijdicks
Publication date
12-07-2022
Publisher
Springer US
Published in
Neurocritical Care / Issue 2/2022
Print ISSN: 1541-6933
Electronic ISSN: 1556-0961
DOI
https://doi.org/10.1007/s12028-022-01560-w

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