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01-03-2021 | Magnetic Resonance Imaging | Review

Advances in imaging technologies for the assessment of peripheral neuropathies in rheumatoid arthritis

Authors: Josefina Gutiérrez, Hugo Sandoval, Iván Pérez-Neri, Antonio Arauz, Juan Carlos López-Hernández, Carlos Pineda

Published in: Rheumatology International | Issue 3/2021

Abstract

Peripheral neuropathy in patients with rheumatoid arthritis is associated with a maladaptive autoimmune response that may cause chronic pain and disability. Nerve conduction studies are the routine method performed when rheumatologists presume its presence. However, this approach is invasive, may not reveal subtle malfunctions in the early stages of the disease, and does not expose abnormalities in structures surrounding the nerves and muscles, limiting the possibility of a timely diagnosis. This work aims to present a narrative review of new technologies for the clinical assessment of peripheral neuropathy in Rheumatoid Arthritis. Through a bibliographic search carried out in five repositories, from 1990 to 2020, we identified three technologies that could detect peripheral nerve lesions and perform quantitative evaluations: (1) magnetic resonance neurography, (2) functional magnetic resonance imaging, and (3) high-resolution ultrasonography of peripheral nerves. We found these tools can overcome the main constraints imposed by the previous electrophysiologic methods, enabling early diagnosis.

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Title: Advances in imaging technologies for the assessment of peripheral neuropathies in rheumatoid arthritis
Authors: Josefina Gutiérrez
Hugo Sandoval
Iván Pérez-Neri
Antonio Arauz
Juan Carlos López-Hernández
Carlos Pineda
Publication date: 01-03-2021
Publisher: Springer Berlin Heidelberg
Keywords: Magnetic Resonance Imaging
Magnetic Resonance Imaging
Peripheral Nervous System Disease
Rheumatoid Arthritis
Published in: Rheumatology International / Issue 3/2021
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI: https://doi.org/10.1007/s00296-020-04780-5

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