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Journal of Neural Transmission
Published in: Journal of Neural Transmission 8/2017

Open Access 01-08-2017 | Neurology and Preclinical Neurological Studies - Review Article

Magnetic resonance imaging for the diagnosis of Parkinson’s disease

Authors: Beatrice Heim, Florian Krismer, Roberto De Marzi, Klaus Seppi

Published in: Journal of Neural Transmission | Issue 8/2017

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Abstract

The differential diagnosis of parkinsonian syndromes is considered one of the most challenging in neurology and error rates in the clinical diagnosis can be high even at specialized centres. Despite several limitations, magnetic resonance imaging (MRI) has undoubtedly enhanced the diagnostic accuracy in the differential diagnosis of neurodegenerative parkinsonism over the last three decades. This review aims to summarize research findings regarding the value of the different MRI techniques, including advanced sequences at high- and ultra-high-field MRI and modern image analysis algorithms, in the diagnostic work-up of Parkinson’s disease. This includes not only the exclusion of alternative diagnoses for Parkinson’s disease such as symptomatic parkinsonism and atypical parkinsonism, but also the diagnosis of early, new onset, and even prodromal Parkinson’s disease.
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Metadata
Title
Magnetic resonance imaging for the diagnosis of Parkinson’s disease
Authors
Beatrice Heim
Florian Krismer
Roberto De Marzi
Klaus Seppi
Publication date
01-08-2017
Publisher
Springer Vienna
Published in
Journal of Neural Transmission / Issue 8/2017
Print ISSN: 0300-9564
Electronic ISSN: 1435-1463
DOI
https://doi.org/10.1007/s00702-017-1717-8

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