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Rheumatology International
Published in: Rheumatology International 8/2010

01-06-2010 | Case Report

Macrophage activation syndrome in malaria

Authors: Rashna Dass, Himesh Barman, Sourabh Gohain Duwarah, Vivek Choudhury, Pankaj Jain, Nayan Mani Deka, Manjula Murari

Published in: Rheumatology International | Issue 8/2010

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Abstract

Macrophage activation syndrome (MAS) is a clinical syndrome caused by an excessive proliferation of T lymphocytes and well-differentiated macrophages; an entity distinct from malignant histiocytosis. Although rheumatologic conditions are the common cause of MAS, a wide range of infections are also seen to cause MAS. We report an adolescent with severe Plasmodium falciparum malaria and MAS. He fulfilled six out of eight criteria required to diagnose hemophagocytic lymphohistiocytosis.
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Metadata
Title
Macrophage activation syndrome in malaria
Authors
Rashna Dass
Himesh Barman
Sourabh Gohain Duwarah
Vivek Choudhury
Pankaj Jain
Nayan Mani Deka
Manjula Murari
Publication date
01-06-2010
Publisher
Springer-Verlag
Published in
Rheumatology International / Issue 8/2010
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-009-1033-1

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