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Published in: Journal of General Internal Medicine 13/2022

22-02-2022 | Macrocytic Anemia | Concise Research Report

Low Frequency of Folate and Vitamin B12 Deficiency in Patients with Marked Macrocytic Anemia

Authors: Shelly Soffer, MD, Orly Efros, MD, Matthew A. Levin, MD, Robert Freeman, RN, MSN, Eyal Zimlichman, MD, David L. Reich, MD, Eyal Klang, MD

Published in: Journal of General Internal Medicine | Issue 13/2022

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Excerpt

A widely used anemia classification system subdivides anemia as microcytic, normocytic, or macrocytic, according to the mean corpuscular volume (MCV) of the red blood cell.1
Literature
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go back to reference Aslinia F, Mazza JJ, Yale SH. Megaloblastic anemia and other causes of macrocytosis. Clinical medicine & research. 2006;4(3):236-41.CrossRef Aslinia F, Mazza JJ, Yale SH. Megaloblastic anemia and other causes of macrocytosis. Clinical medicine & research. 2006;4(3):236-41.CrossRef
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go back to reference Theisen-Toupal J, Horowitz G, Breu A. Low yield of outpatient serum folate testing: eleven years of experience. JAMA internal medicine. 2014;174(10):1696-7.CrossRef Theisen-Toupal J, Horowitz G, Breu A. Low yield of outpatient serum folate testing: eleven years of experience. JAMA internal medicine. 2014;174(10):1696-7.CrossRef
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go back to reference Savage DG, Lindenbaum J, Stabler SP, Allen RH. Sensitivity of serum methylmalonic acid and total homocysteine determinations for diagnosing cobalamin and folate deficiencies. The American journal of medicine. 1994;96(3):239-46.CrossRef Savage DG, Lindenbaum J, Stabler SP, Allen RH. Sensitivity of serum methylmalonic acid and total homocysteine determinations for diagnosing cobalamin and folate deficiencies. The American journal of medicine. 1994;96(3):239-46.CrossRef
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go back to reference Davidson R, Hamilton P. High mean red cell volume: its incidence and significance in routine haematology. Journal of clinical pathology. 1978;31(5):493-8.CrossRef Davidson R, Hamilton P. High mean red cell volume: its incidence and significance in routine haematology. Journal of clinical pathology. 1978;31(5):493-8.CrossRef
Metadata
Title
Low Frequency of Folate and Vitamin B12 Deficiency in Patients with Marked Macrocytic Anemia
Authors
Shelly Soffer, MD
Orly Efros, MD
Matthew A. Levin, MD
Robert Freeman, RN, MSN
Eyal Zimlichman, MD
David L. Reich, MD
Eyal Klang, MD
Publication date
22-02-2022
Publisher
Springer International Publishing
Published in
Journal of General Internal Medicine / Issue 13/2022
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-022-07451-2

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