Published in:
Open Access 01-12-2024 | Lymphoma | Case report
Gastrosplenic fistula due to splenic lymphoma: two case reports and review of the literature
Published in: Journal of Medical Case Reports | Issue 1/2024
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Background
Gastrosplenic fistula is a rare and potentially fatal complication of various conditions. Lymphoma is the most common cause. It can occur spontaneously or after chemotherapy. Gastrosplenic fistula diagnosis can be confused with a splenic abscess because of the presence of air into the mass. The computed tomography identification of the fistulous tract is the key to a right diagnosis. Treatment modalities include surgical resection, chemotherapy, or a combination of both.
Case presentation
Here we report two patients with gastrosplenic fistula due to diffuse large B cell lymphoma. The first patient was a 54-year-old Caucasian woman with an enormous primary splenic diffuse large B cell lymphoma leading to the development of a spontaneous fistula in the stomach. The second patient was a 48-year-old Caucasian male patient with an enormous splenic diffuse large B cell lymphoma complicated by fistula after chemotherapy. Both patients died of septic shock several days after surgery.
Conclusion
Gastrosplenic fistula is a rare complication with a poor-prognosis, for which surgery is currently the preferred treatment.