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Infection
Published in: Infection 6/2015

01-12-2015 | Case Report

Lyme neuroborreliosis in a patient treated with TNF-alpha inhibitor

Authors: Maja Ivartnik Merkac, Janez Tomazic, Franc Strle

Published in: Infection | Issue 6/2015

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Abstract

A 57-year-old woman, receiving TNF-alpha inhibitor adalimumab for psoriasis, presented with early Lyme neuroborreliosis (Bannwarth’s syndrome). Discontinuation of adalimumab and 14-day therapy with ceftriaxone resulted in a smooth course and favorable outcome of Lyme borreliosis. This is the first report on Lyme neuroborreliosis in a patient treated with TNF-alpha inhibitor.
Literature
1.
2.
Stanek G, Fingerle V, Hunfeld KP, Jaulhac B, Kaiser R, Kristoferitsch W, et al. Lyme borreliosis: clinical case definitions for diagnosis and management in Europe. Clin Microbiol Infect. 2011;7:69–79.CrossRef
3.
Wallis D. Infection risk and biologics: current update. Curr Opin Reumatol. 2014;26:404–9.CrossRef
4.
Singh JA, Wells GA, Christensen R, Tanjong Ghogomu E, Maxwell L, Macdonald JK, et al. Adverse effects of biologics: a network meta-analysis and Cochrane overview. Cochrane Database Syst Rev. 2011. doi:10.​1002/​14651858.​CD008794.​pub.​2.
5.
Reiber H, Peter JB. Cerebrospinal fluid analysis: disease-related data patterns and evaluation programs. J Neurol Sci. 2001;184:101–22.CrossRefPubMed
6.
Maraspin V, Lotrič-Furlan S, Cimperman J, Ružić-Sabljić E, Strle F. Erythema migrans in the immunocompromised host. Wien Klin Wochenschr. 1999;111:923–32.PubMed
7.
Fürst B, Glatz M, Kerl H, Müllegger RR. The impact of immunosuppresion on erythema migrans. A retrospective study of clinical presentation, response to treatment and production of Borrelia antibodies in 33 patients. Clin Exp Dermatol. 2006;31:509–14.CrossRefPubMed
8.
Maraspin V, Cimperman J, Lotric-Furlan S, Logar M, Ruzić-Sabljić E, Strle F. Erythema migrans in solid-organ transplant recipients. Clin Infect Dis. 2006;42:1751–4.CrossRefPubMed
9.
Garcia-Monco JC, Frey HM, Villar BF, Golightly MB, Benach JL. Lyme disease concurrent with human immunodeficiency virus infection. Am J Med. 1989;87:325–8.CrossRefPubMed
10.
Rodríguez M, Chou S, Fisher DC, De Girolami U, Amato AA, Marty FM. Lyme meningoradiculitis and myositis after allogeneic hematopoietic stem cell transplantation. Clin Infect Dis. 2005;41:e112–4 Epub 2005 Nov 8.CrossRefPubMed
11.
Harrer T, Geissdörfer W, Schoerner C, Lang E, Helm G. Seronegative Lyme neuroborreliosis in a patient on treatment for chronic lymphatic leukemia. Infection. 2007;35:110–3.CrossRefPubMed
12.
Bremell D, Säll C, Gisslén M, Hagberg L. Lyme neuroborreliosis in HIV-1 positive men successfully treated with oral doxycycline: a case series and literature review. J Med Case Rep. 2011;19:465. doi:10.​1186/​1752-1947-5-465.CrossRef
13.
Cerný R, Machala L, Bojar M, Rozsypal H, Pícha D. Neuroborreliosis in an HIV-1 positive patient. Infection. 2006;34:100–2.CrossRefPubMed
14.
Bonnet N, Guis S, Drancourt M, Brouqui P, Berbis P. Borreliosis in a patient treated with anti-TNFα therapy: first case. J Eur Acad Dermatol Venereol. 2011;25:367–8.CrossRefPubMed
15.
Metadata
Title
Lyme neuroborreliosis in a patient treated with TNF-alpha inhibitor
Authors
Maja Ivartnik Merkac
Janez Tomazic
Franc Strle
Publication date
01-12-2015
Publisher
Springer Berlin Heidelberg
Published in
Infection / Issue 6/2015
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-015-0779-5

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