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Journal of Clinical Immunology
Published in: Journal of Clinical Immunology 1/2017

01-01-2017 | Letter to Editor

Low T Cell Numbers Resembling T−B+ SCID in a Patient with Wiskott–Aldrich Syndrome and the Outcome of Two Hematopoietic Stem Cell Transplantations

Authors: Deniz Cagdas, Selin Aytac, Barış Kuskonmaz, Tadashi Ariga, Mirjam van der Burg, Duygu Uckan Cetinkaya, Özden Sanal, İlhan Tezcan

Published in: Journal of Clinical Immunology | Issue 1/2017

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Excerpt

Dear Editor: …
Literature
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Blundell MP, Worth A, Bouma G, Thrasher AJ. The Wiskott–Aldrich syndrome: the actin cytoskeleton and immune cell function. Dis Markers. 2010;29:157–75.CrossRefPubMedPubMedCentral
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Thrasher AJ. New insights into the biology of Wiskott-Aldrich syndrome (WAS). Hematol Am Soc Hematol Educ Program. 2009;2009:132–8. Review.
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Aiuti A, Biasco L, Scaramuzza S, Ferrua F, Cicalese MP, Baricordi C, et al. Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome. Science. 2013;341:1233151.CrossRefPubMedPubMedCentral
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Sullivan KE, Mullen CA, Blaese RM, Winkelstein JA. A multiinstitutional survey of the Wiskott-Aldrich syndrome. J Pediatr. 1994;125:876–85.CrossRefPubMed
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Cannon JL, Burkhardt JK. Differential roles for Wiskott–Aldrich syndrome protein in immune synapse formation and IL-2 production. J Immunol. 2004;173:1658–62.CrossRefPubMed
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Adriani M, Aoki J, Horai R, Thornton A, Konno A, Kirby M, et al. Impaired in vitro regulatory T cell function associated with Wiskott–Aldrich syndrome. Clin Immunol. 2007;124:41–8.CrossRefPubMedPubMedCentral
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Morales-Tirado V, Johannson S, Hanson E, Howell A, Zhang J, Siminovitch KA, et al. Cutting edge: selective requirement for the Wiskott-Aldrich syndrome protein in cytokine, but not chemokine, secretion by CD4+ T cells. J Immunol. 2004;173:726–30.CrossRefPubMed
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Rawlings SL, Crooks GM, Bockstoce D, Barsky LW, Parkman R, Weinberg KI. Spontaneous apoptosis in lymphocytes from patients with Wiskott-Aldrich syndrome: correlation of accelerated cell death and attenuated bcl-2 expression. Blood. 1999;94(11):3872–82.PubMed
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Inoue R, Kondo N, Kuwabara N, Orii T. Aberrant patterns of immunoglobulin levels in Wiskott-Aldrich syndrome. Scand J Immunol. 1995;41:188–93.CrossRefPubMed
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Borte S, Janzi M, Pan-Hammarström Q, von Döbeln U, Nordvall L, Winiarski J. Placental transfer of maternally-derived IgA precludes the use of guthrie card eluates as a screening tool for primary immunodeficiency diseases. PLoS One. 2012;7(8):e43419.CrossRefPubMedPubMedCentral
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Turul T, Tezcan I, Sanal O. Cernunnos deficiency: a case report. J Investig Allergol Clin Immunol. 2011;21(4):313–6.PubMed
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Dupuis-Girod S, Medioni J, Haddad E, Quartier P, Cavazzana-Calvo M, Le Deist F, et al. Autoimmunity in Wiskott-Aldrich syndrome: risk factors, clinical features, and outcome in a single-center cohort of 55 patients. Pediatrics. 2003;111:e622–7.CrossRefPubMed
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Rappeport JM, O’Reilly RJ, Kapoor N, Parkman R. Hematopoietic stem cell transplantation for severe combined immune deficiency or what the children have taught us. Hematol Oncol Clin N Am. 2011;25(1):17–30.CrossRef
Metadata
Title
Low T Cell Numbers Resembling T−B+ SCID in a Patient with Wiskott–Aldrich Syndrome and the Outcome of Two Hematopoietic Stem Cell Transplantations
Authors
Deniz Cagdas
Selin Aytac
Barış Kuskonmaz
Tadashi Ariga
Mirjam van der Burg
Duygu Uckan Cetinkaya
Özden Sanal
İlhan Tezcan
Publication date
01-01-2017
Publisher
Springer US
Published in
Journal of Clinical Immunology / Issue 1/2017
Print ISSN: 0271-9142
Electronic ISSN: 1573-2592
DOI
https://doi.org/10.1007/s10875-016-0356-4

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