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International Journal of Colorectal Disease

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01-03-2012 | Case Report

Long-term risk of adenocarcinoma post-ileal pouch–anal anastomosis for ulcerative colitis: report of two cases and review of the literature

Authors: James M. O’Riordan, Richard Kirsch, Maryam Mohseni, Robin S. McLeod, Zane Cohen

Published in: International Journal of Colorectal Disease | Issue 3/2012

Excerpt

Restorative proctocolectomy with ileal pouch–anal anastomosis (IPAA) is the preferred surgical option for ulcerative colitis which is refractory to medical therapy. The operation was first described by Parks and Nicholls in 1978, and at that time, it included a mucosectomy and handsewn anastomosis [1]. Since then the double-stapled technique has become increasingly popular because it is technically more straightforward and offers improved functional outcome. However, the disadvantage of this technique is that it leaves behind a small amount of rectal mucosa which has the potential for neoplastic change. However, even if a mucosectomy is performed, there may not be complete removal of all columnar epithelium [2, 3]. …

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Title: Long-term risk of adenocarcinoma post-ileal pouch–anal anastomosis for ulcerative colitis: report of two cases and review of the literature
Authors: James M. O’Riordan
Richard Kirsch
Maryam Mohseni
Robin S. McLeod
Zane Cohen
Publication date: 01-03-2012
Publisher: Springer-Verlag
Published in: International Journal of Colorectal Disease / Issue 3/2012
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI: https://doi.org/10.1007/s00384-011-1243-3

At a glance: The STEP trials

Springer Medicine

Long-term risk of adenocarcinoma post-ileal pouch–anal anastomosis for ulcerative colitis: report of two cases and review of the literature

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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