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Published in: Journal of Interventional Cardiac Electrophysiology 1/2019

01-01-2019

Long-term outcomes after “Zero X-ray” arrhythmia ablation

Authors: Marzia Giaccardi, Giuseppe Mascia, Alessandro Paoletti Perini, Andrea Giomi, Stella Cartei, Massimo Milli

Published in: Journal of Interventional Cardiac Electrophysiology | Issue 1/2019

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Abstract

Purpose

Radiation exposure related to conventional tachyarrhythmia radiofrequency catheter ablation (RFCA) carries small but definite risk for both patients and operators. Today, non-fluoroscopic mapping systems enable to perform catheter ablation with minimal or zero fluoroscopy. The purpose of this study was to evaluate the long-term outcome of patients who had undergone “Zero X-ray” ablation, since no information is available on the very long-term benefits.

Methods

A total of 272 arrhythmias in 266 patients have been treated with catheter ablation by means of a zero-ray approach guided only by a nonconventional mapping system (EnSite NavX™, Ensite™ Velocity™ mapping system; subsequently Ensite™ Precision™ Abbott, St. Paul, MN). Fluoroscopy was never used.

Results

Over a period of 6 years, patients were followed up for an average of 2.9 ± 1.6 years. A 100% rate of acute success was observed in the study population, with a complication rate of 0.8%. Chronic success was achieved in 90.8% of the total number of procedures (272). Patients in whom the same arrhythmia recurred during follow-up underwent to a redo catheter ablation procedure in 60.0% of cases, while the remaining 40.0% underwent pharmacological treatment. A new post-ablation arrhythmia occurred in 7.7% of the sample.

Conclusions

The non-fluoroscopic approach is a feasible and safe alternative to fluoroscopy for arrhythmias ablation. This method ensures low complications rates, high acute procedural success rates, and comparable long-term outcomes with clinical benefits for both patients and physicians. The complete elimination of fluoroscopy during catheter ablation is advantageous and does not reduce patient safety.
Literature
1.
2.
go back to reference Page RL, Joglar JA, Caldwell MA, Calkins H, Conti JB, Deal BJ, et al. 2015 ACC/AHA/HRS guideline for the management of adult patients with supraventricular tachycardia: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. Circulation. 2016;133(14):e506–74.PubMed Page RL, Joglar JA, Caldwell MA, Calkins H, Conti JB, Deal BJ, et al. 2015 ACC/AHA/HRS guideline for the management of adult patients with supraventricular tachycardia: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. Circulation. 2016;133(14):e506–74.PubMed
3.
go back to reference Theocharopoulos N, Damilakis J, Perisinakis K, Manios E, Vardas P, Gourtsoyiannis N. Occupational exposure in the electrophysiology laboratory: quantifying and minimizing radiation burden. Br J Radiol. 2006;79:644–51.CrossRefPubMed Theocharopoulos N, Damilakis J, Perisinakis K, Manios E, Vardas P, Gourtsoyiannis N. Occupational exposure in the electrophysiology laboratory: quantifying and minimizing radiation burden. Br J Radiol. 2006;79:644–51.CrossRefPubMed
4.
go back to reference Clay MA, Campbell RM, Strieper M, Frias PA, Stevens M, Mahle WT. Long term risk of fatal malignancy following pediatric radiofrequency ablation. Am J Cardiol. 2008;102:913–5.CrossRefPubMed Clay MA, Campbell RM, Strieper M, Frias PA, Stevens M, Mahle WT. Long term risk of fatal malignancy following pediatric radiofrequency ablation. Am J Cardiol. 2008;102:913–5.CrossRefPubMed
5.
go back to reference Calkins H, Niklason L, Sousa J, el-Atassi R, Langberg J, Morady F. Radiation exposure during radiofrequency catheter ablation of accessory atrioventricular connections. Circulation. 1991;84:2376–82.CrossRefPubMed Calkins H, Niklason L, Sousa J, el-Atassi R, Langberg J, Morady F. Radiation exposure during radiofrequency catheter ablation of accessory atrioventricular connections. Circulation. 1991;84:2376–82.CrossRefPubMed
6.
go back to reference Hirshfeld JW Jr, Balter S, Brinker JA, Kern MJ, Klein LW, Lindsay BD, et al. ACCF/AHA/HRS/SCAI clinical competence statement on physician knowledge to optimize patient safety and image quality in fluoroscopically guided invasive cardiovascular procedures: a report of the American College of Cardiology Foundation/American Heart Association/American College of Physicians Task Force on Clinical Competence and Training. Circulation. 2005;111(4):511–32.CrossRefPubMed Hirshfeld JW Jr, Balter S, Brinker JA, Kern MJ, Klein LW, Lindsay BD, et al. ACCF/AHA/HRS/SCAI clinical competence statement on physician knowledge to optimize patient safety and image quality in fluoroscopically guided invasive cardiovascular procedures: a report of the American College of Cardiology Foundation/American Heart Association/American College of Physicians Task Force on Clinical Competence and Training. Circulation. 2005;111(4):511–32.CrossRefPubMed
7.
go back to reference Drago F, Silvetti MS, DiPino A, Grutter G, Bevilacqua M, Leibovich S. Exclusion of fluoroscopy during ablation treatment of right accessory pathway in children. J Cardiovasc Electrophysiol. 2002;13:778–82.CrossRefPubMed Drago F, Silvetti MS, DiPino A, Grutter G, Bevilacqua M, Leibovich S. Exclusion of fluoroscopy during ablation treatment of right accessory pathway in children. J Cardiovasc Electrophysiol. 2002;13:778–82.CrossRefPubMed
8.
go back to reference Kammeraad J, Udinkten Cate F, Simmers T, Emmel M, Wittkampf FHM, Sreeram N. Radiofrequency catheter ablation of atrioventricular nodal reentrant tachycardia in children aided by the LocaLisa mapping system. Europace. 2004;6:209–14.CrossRefPubMed Kammeraad J, Udinkten Cate F, Simmers T, Emmel M, Wittkampf FHM, Sreeram N. Radiofrequency catheter ablation of atrioventricular nodal reentrant tachycardia in children aided by the LocaLisa mapping system. Europace. 2004;6:209–14.CrossRefPubMed
9.
go back to reference Papagiannis J, Tsoutsinos A, Kirvassilis G, Sofianidou I, Koussi T, Laskari C, et al. Nonfluoroscopic catheter navigation for radiofrequency catheter ablation of supraventricular tachycardia in children. Pacing Clin Electrophysiol. 2006;29:971–8.CrossRefPubMed Papagiannis J, Tsoutsinos A, Kirvassilis G, Sofianidou I, Koussi T, Laskari C, et al. Nonfluoroscopic catheter navigation for radiofrequency catheter ablation of supraventricular tachycardia in children. Pacing Clin Electrophysiol. 2006;29:971–8.CrossRefPubMed
10.
go back to reference Smith G, Clark JM. Elimination of fluoroscopy use in a pediatric electrophysiology laboratory utilizing three-dimensional mapping. Pacing Clin Electrophysiol. 2007;30:510–8.CrossRefPubMed Smith G, Clark JM. Elimination of fluoroscopy use in a pediatric electrophysiology laboratory utilizing three-dimensional mapping. Pacing Clin Electrophysiol. 2007;30:510–8.CrossRefPubMed
11.
go back to reference Papez AL, Al-Ahdab M, Dick M, Fischbach PS. Impact of a computer assisted navigation system on radiation exposure during pediatric ablation procedures. J Interv Card Electrophysiol. 2007;19:121–7.CrossRefPubMed Papez AL, Al-Ahdab M, Dick M, Fischbach PS. Impact of a computer assisted navigation system on radiation exposure during pediatric ablation procedures. J Interv Card Electrophysiol. 2007;19:121–7.CrossRefPubMed
12.
go back to reference Tuzcu V. A nonfluoroscopic approach for electrophysiology and catheter ablation procedures using a three-dimensional navigation system. Pacing Clin Electrophysiol. 2007;30:519–25.CrossRefPubMed Tuzcu V. A nonfluoroscopic approach for electrophysiology and catheter ablation procedures using a three-dimensional navigation system. Pacing Clin Electrophysiol. 2007;30:519–25.CrossRefPubMed
13.
go back to reference Casella M, Pelargonio G, Dello Russo A, Riva S, Bartoletti S, Santangeli P, et al. “Near-zero” fluoroscopic exposure in supraventricular arrhythmia ablation using the EnSite VelocityTM mapping system: personal experience and review of the literature. J Interv Card Electrophysiol. 2011;31:109–18.CrossRefPubMed Casella M, Pelargonio G, Dello Russo A, Riva S, Bartoletti S, Santangeli P, et al. “Near-zero” fluoroscopic exposure in supraventricular arrhythmia ablation using the EnSite VelocityTM mapping system: personal experience and review of the literature. J Interv Card Electrophysiol. 2011;31:109–18.CrossRefPubMed
14.
go back to reference Giaccardi M, Del Rosso A, Guarnaccia V, Ballo P, Mascia G, Chiodi L, et al. Near-zero x-ray in arrhythmia ablation using a 3-dimensional electroanatomic mapping system: a multicenter experience. Heart Rhythm. 2016;13:150–6.CrossRefPubMed Giaccardi M, Del Rosso A, Guarnaccia V, Ballo P, Mascia G, Chiodi L, et al. Near-zero x-ray in arrhythmia ablation using a 3-dimensional electroanatomic mapping system: a multicenter experience. Heart Rhythm. 2016;13:150–6.CrossRefPubMed
15.
go back to reference Yang L, Sun G, Chen X, Chen G, Yang S, Guo P. Meta-analysis of zero or near-zero fluoroscopy use during ablation of cardiac arrhythmias. Am J Cardiol. 2016;118:1511–8.CrossRefPubMed Yang L, Sun G, Chen X, Chen G, Yang S, Guo P. Meta-analysis of zero or near-zero fluoroscopy use during ablation of cardiac arrhythmias. Am J Cardiol. 2016;118:1511–8.CrossRefPubMed
16.
go back to reference Maskoun W, Pino MI, Ayoub K, Llanos OL, Almomani A, Nairooz R, et al. Incidence of atrial fibrillation after atrial flutter ablation. JACC: Clin Electrophysiol. 2016;2(6):682–90. Maskoun W, Pino MI, Ayoub K, Llanos OL, Almomani A, Nairooz R, et al. Incidence of atrial fibrillation after atrial flutter ablation. JACC: Clin Electrophysiol. 2016;2(6):682–90.
17.
go back to reference Rotter M, Takahashi Y, Sanders P, Haïssaguerre M, Jaïs P, Hsu LF, et al. Reduction of fluoroscopy exposure and procedure duration during ablation of atrial fibrillation using a novel anatomical navigation system. Eur Heart J. 2005;26:1415–21.CrossRefPubMed Rotter M, Takahashi Y, Sanders P, Haïssaguerre M, Jaïs P, Hsu LF, et al. Reduction of fluoroscopy exposure and procedure duration during ablation of atrial fibrillation using a novel anatomical navigation system. Eur Heart J. 2005;26:1415–21.CrossRefPubMed
18.
go back to reference Sporton SC, Earley MJ, Nathan AW, Schilling RJ. Electroanatomic versus fluoroscopic mapping for catheter ablation procedures: a prospective randomized study. J Cardiovasc Electrophysiol. 2004;15(3):310–5.CrossRefPubMed Sporton SC, Earley MJ, Nathan AW, Schilling RJ. Electroanatomic versus fluoroscopic mapping for catheter ablation procedures: a prospective randomized study. J Cardiovasc Electrophysiol. 2004;15(3):310–5.CrossRefPubMed
19.
go back to reference Pérez FJ, Schubert CM, Parvez B, Pathak V, Ellenbogen KA, Wood MA. Term outcomes after catheter ablation of cavo-tricuspid isthmus dependent atrial flutter. A meta-analysis. Circ Arrhythm Electrophysiol. 2009;2:393–401.CrossRefPubMed Pérez FJ, Schubert CM, Parvez B, Pathak V, Ellenbogen KA, Wood MA. Term outcomes after catheter ablation of cavo-tricuspid isthmus dependent atrial flutter. A meta-analysis. Circ Arrhythm Electrophysiol. 2009;2:393–401.CrossRefPubMed
20.
go back to reference Buddhe S, Singh H, Du W, Karpawich PP. Radiofrequency and cryoablation therapies for supraventricular arrhythmias in the young: five-year review of efficacies. Pacing Clin Electrophysiol. 2012;35(6):711–7.CrossRefPubMed Buddhe S, Singh H, Du W, Karpawich PP. Radiofrequency and cryoablation therapies for supraventricular arrhythmias in the young: five-year review of efficacies. Pacing Clin Electrophysiol. 2012;35(6):711–7.CrossRefPubMed
21.
go back to reference Scaglione M, Ebrille E, Caponi D, Siboldi A, Bertero G, Di Donna P, et al. Zero-fluoroscopy ablation of accessory pathways in children and adolescents: CARTO3 electroanatomic mapping combined with RF and cryoenergy. Pacing Clin Electrophysiol. 2015;38(6):675–81.CrossRefPubMed Scaglione M, Ebrille E, Caponi D, Siboldi A, Bertero G, Di Donna P, et al. Zero-fluoroscopy ablation of accessory pathways in children and adolescents: CARTO3 electroanatomic mapping combined with RF and cryoenergy. Pacing Clin Electrophysiol. 2015;38(6):675–81.CrossRefPubMed
22.
go back to reference Casella M, Dello Russo A, Pelargonio G, Del Greco M, Zingarini G, Piacenti M, et al. Near zerO fluoroscopic exPosure during catheter ablAtion of supRavenTricular arrhYthmias: the NO-PARTY multicentre randomized trial. Europace. 2016;18:1565–72.CrossRefPubMed Casella M, Dello Russo A, Pelargonio G, Del Greco M, Zingarini G, Piacenti M, et al. Near zerO fluoroscopic exPosure during catheter ablAtion of supRavenTricular arrhYthmias: the NO-PARTY multicentre randomized trial. Europace. 2016;18:1565–72.CrossRefPubMed
23.
go back to reference Estner HL, Deisenhofer I, Luik A, Ndrepepa G, von Bary C, Zrenner B, et al. Electrical isolation of pulmonary veins in patients with atrial fibrillation: reduction of fluoroscopy exposure and procedure duration by the use of a non-fluoroscopic navigation system (NavX). Europace. 2006;8(8):583–7.CrossRefPubMed Estner HL, Deisenhofer I, Luik A, Ndrepepa G, von Bary C, Zrenner B, et al. Electrical isolation of pulmonary veins in patients with atrial fibrillation: reduction of fluoroscopy exposure and procedure duration by the use of a non-fluoroscopic navigation system (NavX). Europace. 2006;8(8):583–7.CrossRefPubMed
24.
go back to reference Lindsay BD, Eichling JO, Ambos HD, Cain ME. Radiation exposure to patients and medical personnel during radiofrequency catheter ablation for supraventricular tachycardia. Am J Cardiol. 1992;70:218–23.CrossRefPubMed Lindsay BD, Eichling JO, Ambos HD, Cain ME. Radiation exposure to patients and medical personnel during radiofrequency catheter ablation for supraventricular tachycardia. Am J Cardiol. 1992;70:218–23.CrossRefPubMed
25.
go back to reference Rosenthal LS, Mahesh M, Beck TJ, Saul JP, Miller JM, Kay N, et al. Predictors of fluoroscopy time and estimated radiation exposure during radiofrequency catheter ablation procedures. Am J Cardiol. 1998;82(4):451–8.CrossRefPubMed Rosenthal LS, Mahesh M, Beck TJ, Saul JP, Miller JM, Kay N, et al. Predictors of fluoroscopy time and estimated radiation exposure during radiofrequency catheter ablation procedures. Am J Cardiol. 1998;82(4):451–8.CrossRefPubMed
26.
go back to reference Kovoor P, Ricciardello M, Collins L, Uther JB, Ross DL. Risk to patients from radiation associated with radiofrequency ablation for supraventricular tachycardia. Circulation. 1998;98:1534–40.CrossRefPubMed Kovoor P, Ricciardello M, Collins L, Uther JB, Ross DL. Risk to patients from radiation associated with radiofrequency ablation for supraventricular tachycardia. Circulation. 1998;98:1534–40.CrossRefPubMed
27.
go back to reference Perisinakis K, Damilakis J, Theocharopoulos N, Manios E, Vardas P, Gourtsoyiannis N. Accurate assessment of patient effective radiation dose and associated detriment risk from radiofrequency catheter ablation procedures. Circulation. 2001;104:58–62.CrossRefPubMed Perisinakis K, Damilakis J, Theocharopoulos N, Manios E, Vardas P, Gourtsoyiannis N. Accurate assessment of patient effective radiation dose and associated detriment risk from radiofrequency catheter ablation procedures. Circulation. 2001;104:58–62.CrossRefPubMed
28.
go back to reference Darrat Y, Morales G, Di BL, Natale A, Elayi CS. How to achieve durable pulmonary vein antral isolation? J Atrial Fibrillation. 2014;6(6):1039. Darrat Y, Morales G, Di BL, Natale A, Elayi CS. How to achieve durable pulmonary vein antral isolation? J Atrial Fibrillation. 2014;6(6):1039.
29.
go back to reference Picano E, Vañó E, Rehani MM, Cuocolo A, Mont L, Bodi V, et al. The appropriate and justified use of medical radiation in cardiovascular imaging: a position document of the ESC Associations of Cardiovascular Imaging, Percutaneous Cardiovascular Interventions and Electrophysiology. Eur Heart J. 2014;35(10):665–72.CrossRefPubMed Picano E, Vañó E, Rehani MM, Cuocolo A, Mont L, Bodi V, et al. The appropriate and justified use of medical radiation in cardiovascular imaging: a position document of the ESC Associations of Cardiovascular Imaging, Percutaneous Cardiovascular Interventions and Electrophysiology. Eur Heart J. 2014;35(10):665–72.CrossRefPubMed
30.
go back to reference Gaita F, Guerra PG, Battaglia A, Anselmino M. The dream of near-zero X-rays ablation comes true. Eur Heart J. 2016;37(36):2749–55.CrossRefPubMed Gaita F, Guerra PG, Battaglia A, Anselmino M. The dream of near-zero X-rays ablation comes true. Eur Heart J. 2016;37(36):2749–55.CrossRefPubMed
31.
go back to reference Reddy VY, Morales G, Ahmed H, Neuzil P, Dukkipati S, Kim S, et al. Catheter ablation of atrial fibrillation without the use of fluoroscopy. Heart Rhythm. 2010;7:1644–53.CrossRefPubMed Reddy VY, Morales G, Ahmed H, Neuzil P, Dukkipati S, Kim S, et al. Catheter ablation of atrial fibrillation without the use of fluoroscopy. Heart Rhythm. 2010;7:1644–53.CrossRefPubMed
Metadata
Title
Long-term outcomes after “Zero X-ray” arrhythmia ablation
Authors
Marzia Giaccardi
Giuseppe Mascia
Alessandro Paoletti Perini
Andrea Giomi
Stella Cartei
Massimo Milli
Publication date
01-01-2019
Publisher
Springer US
Published in
Journal of Interventional Cardiac Electrophysiology / Issue 1/2019
Print ISSN: 1383-875X
Electronic ISSN: 1572-8595
DOI
https://doi.org/10.1007/s10840-018-0390-7

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