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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 6/2019

01-06-2019 | Liver Transplantation | Hepatobiliary Tumors

Living Donor Liver Transplant for Hepatocellular Carcinoma

Authors: Vijay Subramanian, MD, William Chapman, MD

Published in: Annals of Surgical Oncology | Issue 6/2019

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Excerpt

Hepatocellular carcinoma (HCC) is the most common cancer in the liver and is the third leading cause of cancer-related deaths worldwide. Given the predilection of HCC in patients with underlying chronic disease, the majority of patients diagnosed with HCC are not resectable at the time of diagnosis. …
Literature
1.
Mazzaferro V, Regalia E, Doci R et al. Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N. Engl. J. Med. 1996; 334:693–699.CrossRefPubMed
2.
Yao FY, Ferrell L, Bass NM et al. Liver transplantation for hepatocellular carcinoma: expansion of the tumor size limits does not adversely impact survival. Hepatology. 2001; 33:1394–1403.CrossRefPubMed
3.
Chapman WC, Majella Doyle MB, Stuart JE et al. Outcomes of neoadjuvant transarterial chemoembolization to downstage hepatocellular carcinoma before liver transplantation. Ann. Surg. 2008;248:617–625.PubMed
4.
Chapman WC, Garcia-Aroz S, Vachharajani N, et al. Liver transplantation for advanced hepatocellular carcinoma after downstaging without up-front stage restrictions. J. Am. Coll. Surg. 2017;224:610–621.CrossRefPubMed
5.
Llovet JM, Fuster J, Bruix J. Intention-to-treat analysis of surgical treatment for early hepatocellular carcinoma: resection versus transplantation. Hepatology. 1999;30:1434–1440.CrossRefPubMed
6.
Yao FY, Bass NM, Nikolai B, et al. A follow-up analysis of the pattern and predictors of dropout from the waiting list for liver transplantation in patients with hepatocellular carcinoma: implications for the current organ allocation policy. Liver Transpl. 2003;9:684–692.CrossRefPubMed
7.
Wong TCL, Ng KKC, Fung JYY, et al. Long-term survival outcome between living donor and deceased donor liver transplant for hepatocellular carcinoma: Intention-to-treat and propensity score matching analyses. Ann Surg Oncol. Epub 8 Feb 2019. https://​doi.​org/​10.​1245/​s10434-019-07206-0.
8.
Bhangui P, Vibert E, Majno P et al. Intention-to-treat analysis of liver transplantation for hepatocellular carcinoma: living versus deceased donor transplantation. Hepatology. 2011;53:1570–1579.CrossRefPubMed
9.
Takada Y, Ito T, Ueda M, et al. Living donor liver transplantation for patients with HCC exceeding the Milan criteria: a proposal of expanded criteria. Dig Dis. 2007;25:299–302.CrossRefPubMed
10.
Lee SD, Lee B, Kim SH et al. Proposal of new expanded selection criteria using total tumor size and (18)F-fluorodeoxyglucose - positron emission tomography/computed tomography for living donor liver transplantation in patients with hepatocellular carcinoma: The National Cancer Center Korea criteria. World J. Transplant. 2016;6:411–422.CrossRefPubMedPubMedCentral
11.
Kim JM, Kwon CH, Joh JW, et al. Expanded criteria for liver transplantation in patients with hepatocellular carcinoma. Transplant Proc. 2014;46:726–729.CrossRefPubMed
Metadata
Title
Living Donor Liver Transplant for Hepatocellular Carcinoma
Authors
Vijay Subramanian, MD
William Chapman, MD
Publication date
01-06-2019
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue 6/2019
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-019-07250-w

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