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Open Access 01-02-2022 | Liver Surgery

Technical feasibility and short-term outcomes of laparoscopic isolated caudate lobe resection: an IgoMILS (Italian Group of Minimally Invasive Liver Surgery) registry-based study

Authors: Andrea Ruzzenente, Andrea Ciangherotti, Luca Aldrighetti, Giuseppe Maria Ettorre, Luciano De Carlis, Alessandro Ferrero, Raffaele Dalla Valle, Giuseppe Tisone, Alfredo Guglielmi, The IgoMILS – Sg1 Group

Published in: Surgical Endoscopy | Issue 2/2022

Abstract

Background

Although isolated caudate lobe (CL) liver resection is not a contraindication for minimally invasive liver surgery (MILS), feasibility and safety of the procedure are still poorly investigated. To address this gap, we evaluate data on the Italian prospective maintained database on laparoscopic liver surgery (IgoMILS) and compare outcomes between MILS and open group.

Methods

Perioperative data of patients with malignancies, as colorectal liver metastases (CRLM), hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC), non-colorectal liver metastases (NCRLM) and benign liver disease, were retrospectively analyzed. A propensity score matching (PSM) analysis was performed to balance the potential selection bias for MILS and open group.

Results

A total of 224 patients were included in the study, 47 and 177 patients underwent MILS and open isolated CL resection, respectively. The overall complication rate was comparable between the two groups; however, severe complication rate (Dindo–Clavien grade ≥ 3) was lower in the MILS group (0% versus 6.8%, P = ns). In-hospital mortality was 0% in both groups and mean hospital stay was significantly shorter in the MILS group (P = 0.01). After selection of 42 MILS and 43 open CL resections by PSM analysis, intraoperative and postoperative outcomes remained similar except for the hospital stay which was not significantly shorter in MILS group.

Conclusions

This multi-institutional cohort study shows that MILS CL resection is feasible and safe. The surgical procedure can be technically demanding compared to open resection, whereas good perioperative outcomes can be achieved in highly selected patients.

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Title: Technical feasibility and short-term outcomes of laparoscopic isolated caudate lobe resection: an IgoMILS (Italian Group of Minimally Invasive Liver Surgery) registry-based study
Authors: Andrea Ruzzenente
Andrea Ciangherotti
Luca Aldrighetti
Giuseppe Maria Ettorre
Luciano De Carlis
Alessandro Ferrero
Raffaele Dalla Valle
Giuseppe Tisone
Alfredo Guglielmi
The IgoMILS – Sg1 Group
Publication date: 01-02-2022
Publisher: Springer US
Keywords: Liver Surgery
Liver Surgery
Published in: Surgical Endoscopy / Issue 2/2022
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-021-08434-w

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Technical feasibility and short-term outcomes of laparoscopic isolated caudate lobe resection: an IgoMILS (Italian Group of Minimally Invasive Liver Surgery) registry-based study

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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