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Published in: Langenbeck's Archives of Surgery 4/2019

01-06-2019 | Laparoscopy | Original Article

Laparoscopic versus open hemihepatectomy—a cost analysis after propensity score matching

Authors: S. Wabitsch, A. Kästner, P. K. Haber, L. Feldbrügge, T. Winklmann, S. Werner, J. Pratschke, Moritz Schmelzle

Published in: Langenbeck's Archives of Surgery | Issue 4/2019

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Abstract

Introduction

Cost efficiency is important for hospitals in order to provide high-quality health care for all patients. As hemihepatectomies are increasingly being performed laparoscopically, the aims of this study were to evaluate the costs of laparoscopic hemihepatectomy and to compare them to conventional open techniques.

Patients and methods

This is a retrospective analysis of clinical outcomes and financial calculations of all patients who underwent hemihepatectomy between January 2015 and December 2016 at the Department of Surgery, Campus Charité Mitte and Campus Charité Virchow-Klinikum, Berlin, Germany, being allocated to the DRG (diagnosis-related group) H01A (complex operations of the liver and pancreas with complex intensive care treatment) or H01B (operations of the liver and pancreas without complex intensive care treatment). To overcome selection bias, a 1:1 propensity score matching (PSM) analysis was performed.

Results

After PSM, a total of 64 patients were identified; 32 patients underwent laparoscopic hemihepatectomy (LH); and 32 patients received open hemihepatectomy (OH). After PSM, no significant differences were observed in clinical baseline characteristics. The duration of surgery was significantly longer for patients undergoing LH compared to OH (LH, 334 min, 186–655 min; OH, 274 min, 176–454 min; p = 0.005). Patients in the LH group had a significantly shortened median hospital stay of 5 d, when compared to OH (LH, 9.5 d, 3–35 d; OH, 14.5 d, 7–37d; p = 0.005). We observed a significant higher rate of postoperative complication in the OH group (p = 0.022). Cost analysis showed median overall costs of 17,369.85€ in the LH group and 16,103.64€ in the OH group (p = 0.390).

Conclusion

Our data suggest that higher intraoperative costs of laparoscopic liver surgery, e.g., for surgical devices and due to longer operation times, are compensated by fewer postoperative complications and consecutive shorter length of stay when compared with OH.
Literature
1.
go back to reference Lacy AM, García-Valdecasas JC, Piqué JM, Delgado S, Campo E, Bordas JM et al (1995) Short-term outcome analysis of a randomized study comparing laparoscopic vs open colectomy for colon cancer. Surg Endosc 9(10):1101–1105CrossRefPubMed Lacy AM, García-Valdecasas JC, Piqué JM, Delgado S, Campo E, Bordas JM et al (1995) Short-term outcome analysis of a randomized study comparing laparoscopic vs open colectomy for colon cancer. Surg Endosc 9(10):1101–1105CrossRefPubMed
2.
go back to reference Schwenk W, Böhm B, Müller JM (1998) Postoperative pain and fatigue after laparoscopic or conventional colorectal resections. A prospective randomized trial. Surg Endosc 12(9):1131–1136CrossRefPubMed Schwenk W, Böhm B, Müller JM (1998) Postoperative pain and fatigue after laparoscopic or conventional colorectal resections. A prospective randomized trial. Surg Endosc 12(9):1131–1136CrossRefPubMed
3.
go back to reference Beppu T, Wakabayashi G, Hasegawa K, Gotohda N, Mizuguchi T, Takahashi Y, Hirokawa F, Taniai N, Watanabe M, Katou M, Nagano H, Honda G, Baba H, Kokudo N, Konishi M, Hirata K, Yamamoto M, Uchiyama K, Uchida E, Kusachi S, Kubota K, Mori M, Takahashi K, Kikuchi K, Miyata H, Takahara T, Nakamura M, Kaneko H, Yamaue H, Miyazaki M, Takada T (2015) Long-term and perioperative outcomes of laparoscopic versus open liver resection for colorectal liver metastases with propensity score matching: a multi-institutional Japanese study. J Hepatobiliary Pancreat Sci 22(10):711–720CrossRefPubMed Beppu T, Wakabayashi G, Hasegawa K, Gotohda N, Mizuguchi T, Takahashi Y, Hirokawa F, Taniai N, Watanabe M, Katou M, Nagano H, Honda G, Baba H, Kokudo N, Konishi M, Hirata K, Yamamoto M, Uchiyama K, Uchida E, Kusachi S, Kubota K, Mori M, Takahashi K, Kikuchi K, Miyata H, Takahara T, Nakamura M, Kaneko H, Yamaue H, Miyazaki M, Takada T (2015) Long-term and perioperative outcomes of laparoscopic versus open liver resection for colorectal liver metastases with propensity score matching: a multi-institutional Japanese study. J Hepatobiliary Pancreat Sci 22(10):711–720CrossRefPubMed
4.
go back to reference Parks KR, Kuo Y-H, Davis JM, O’ Brien B, Hagopian EJ (2014) Laparoscopic versus open liver resection: a meta-analysis of long-term outcome. HPB (Oxford) 16(2):109–118CrossRef Parks KR, Kuo Y-H, Davis JM, O’ Brien B, Hagopian EJ (2014) Laparoscopic versus open liver resection: a meta-analysis of long-term outcome. HPB (Oxford) 16(2):109–118CrossRef
5.
go back to reference Okuno M, Goumard C, Mizuno T, Omichi K, Tzeng CD, Chun YS et al (2017) Operative and short-term oncologic outcomes of laparoscopic versus open liver resection for colorectal liver metastases located in the posterosuperior liver: a propensity score matching analysis. Surg Endosc [zitiert 16. Januar 2018]; Verfügbar unter: http://europepmc.org/abstract/med/28917012 Okuno M, Goumard C, Mizuno T, Omichi K, Tzeng CD, Chun YS et al (2017) Operative and short-term oncologic outcomes of laparoscopic versus open liver resection for colorectal liver metastases located in the posterosuperior liver: a propensity score matching analysis. Surg Endosc [zitiert 16. Januar 2018]; Verfügbar unter: http://​europepmc.​org/​abstract/​med/​28917012
6.
go back to reference Ahn KS, Kang KJ, Kim YH, Kim T-S, Lim TJ (2014) A propensity score-matched case-control comparative study of laparoscopic and open liver resection for hepatocellular carcinoma. J Laparoendosc Adv Surg Tech A 24(12):872–877CrossRefPubMed Ahn KS, Kang KJ, Kim YH, Kim T-S, Lim TJ (2014) A propensity score-matched case-control comparative study of laparoscopic and open liver resection for hepatocellular carcinoma. J Laparoendosc Adv Surg Tech A 24(12):872–877CrossRefPubMed
7.
go back to reference Aikawa M, Miyazawa M, Okamoto K, Toshimitsu Y, Okada K, Ueno Y, Yamaguchi S, Koyama I (2012) Single-port laparoscopic hepatectomy: technique, safety, and feasibility in a clinical case series. Surg Endosc 26(6):1696–1701CrossRefPubMed Aikawa M, Miyazawa M, Okamoto K, Toshimitsu Y, Okada K, Ueno Y, Yamaguchi S, Koyama I (2012) Single-port laparoscopic hepatectomy: technique, safety, and feasibility in a clinical case series. Surg Endosc 26(6):1696–1701CrossRefPubMed
8.
go back to reference Sotiropoulos GC, Prodromidou A, Machairas N (2017) Meta-analysis of laparoscopic vs open liver resection for hepatocellular carcinoma: the European experience. J BUON 22(5):1160–1171PubMed Sotiropoulos GC, Prodromidou A, Machairas N (2017) Meta-analysis of laparoscopic vs open liver resection for hepatocellular carcinoma: the European experience. J BUON 22(5):1160–1171PubMed
9.
go back to reference Vanounou T, Steel JL, Nguyen KT, Tsung A, Marsh JW, Geller DA, Gamblin TC (2010) Comparing the clinical and economic impact of laparoscopic versus open liver resection. Ann Surg Oncol 17(4):998–1009CrossRefPubMed Vanounou T, Steel JL, Nguyen KT, Tsung A, Marsh JW, Geller DA, Gamblin TC (2010) Comparing the clinical and economic impact of laparoscopic versus open liver resection. Ann Surg Oncol 17(4):998–1009CrossRefPubMed
10.
go back to reference Dokmak S, Raut V, Aussilhou B, Ftériche FS, Farges O, Sauvanet A, Belghiti J (2014) Laparoscopic left lateral resection is the gold standard for benign liver lesions: a case–control study. HPB (Oxford) 16(2):183–187CrossRef Dokmak S, Raut V, Aussilhou B, Ftériche FS, Farges O, Sauvanet A, Belghiti J (2014) Laparoscopic left lateral resection is the gold standard for benign liver lesions: a case–control study. HPB (Oxford) 16(2):183–187CrossRef
12.
go back to reference Clavien PA, Barkun J, de Oliveira ML, Vauthey JN, Dindo D, Schulick RD, de Santibañes E, Pekolj J, Slankamenac K, Bassi C, Graf R, Vonlanthen R, Padbury R, Cameron JL, Makuuchi M (2009) The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg 250(2):187–196CrossRefPubMed Clavien PA, Barkun J, de Oliveira ML, Vauthey JN, Dindo D, Schulick RD, de Santibañes E, Pekolj J, Slankamenac K, Bassi C, Graf R, Vonlanthen R, Padbury R, Cameron JL, Makuuchi M (2009) The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg 250(2):187–196CrossRefPubMed
13.
go back to reference Abu Hilal M, Di Fabio F, Syed S, Wiltshire R, Dimovska E, Turner D et al (2013) Assessment of the financial implications for laparoscopic liver surgery: a single-centre UK cost analysis for minor and major hepatectomy. Surg Endosc 27(7):2542–2550CrossRefPubMed Abu Hilal M, Di Fabio F, Syed S, Wiltshire R, Dimovska E, Turner D et al (2013) Assessment of the financial implications for laparoscopic liver surgery: a single-centre UK cost analysis for minor and major hepatectomy. Surg Endosc 27(7):2542–2550CrossRefPubMed
14.
go back to reference Cannon RM, Scoggins CR, Callender GG, Quillo A, McMasters KM, Martin RCG (2013) Financial comparison of laparoscopic versus open hepatic resection using deviation-based cost modeling. Ann Surg Oncol 20(9):2887–2892CrossRefPubMed Cannon RM, Scoggins CR, Callender GG, Quillo A, McMasters KM, Martin RCG (2013) Financial comparison of laparoscopic versus open hepatic resection using deviation-based cost modeling. Ann Surg Oncol 20(9):2887–2892CrossRefPubMed
15.
go back to reference Schemmer P, Bruns H, Weitz J, Schmidt J, Büchler MW (2008) Liver transection using vascular stapler: a review. HPB (Oxford) 10(4):249–252CrossRef Schemmer P, Bruns H, Weitz J, Schmidt J, Büchler MW (2008) Liver transection using vascular stapler: a review. HPB (Oxford) 10(4):249–252CrossRef
16.
go back to reference Rahbari NN, Elbers H, Koch M, Vogler P, Striebel F, Bruckner T, Mehrabi A, Schemmer P, Büchler MW, Weitz J (2014) Randomized clinical trial of stapler versus clamp-crushing transection in elective liver resection. Br J Surg 101(3):200–207CrossRefPubMed Rahbari NN, Elbers H, Koch M, Vogler P, Striebel F, Bruckner T, Mehrabi A, Schemmer P, Büchler MW, Weitz J (2014) Randomized clinical trial of stapler versus clamp-crushing transection in elective liver resection. Br J Surg 101(3):200–207CrossRefPubMed
17.
go back to reference Bhojani FD, Fox A, Pitzul K, Gallinger S, Wei A, Moulton C-A, Okrainec A, Cleary SP (2012) Clinical and economic comparison of laparoscopic to open liver resections using a 2-to-1 matched pair analysis: an institutional experience. J Am Coll Surg 214(2):184–195CrossRefPubMed Bhojani FD, Fox A, Pitzul K, Gallinger S, Wei A, Moulton C-A, Okrainec A, Cleary SP (2012) Clinical and economic comparison of laparoscopic to open liver resections using a 2-to-1 matched pair analysis: an institutional experience. J Am Coll Surg 214(2):184–195CrossRefPubMed
18.
go back to reference Stoot JHMB, van Dam RM, Coelen RJS, Winkens B, Olde Damink SWM, Bemelmans MHA et al (2012) The introduction of a laparoscopic liver surgery programme: a cost analysis of initial experience in a university hospital. Scand J Surg 101(1):32–37CrossRefPubMed Stoot JHMB, van Dam RM, Coelen RJS, Winkens B, Olde Damink SWM, Bemelmans MHA et al (2012) The introduction of a laparoscopic liver surgery programme: a cost analysis of initial experience in a university hospital. Scand J Surg 101(1):32–37CrossRefPubMed
Metadata
Title
Laparoscopic versus open hemihepatectomy—a cost analysis after propensity score matching
Authors
S. Wabitsch
A. Kästner
P. K. Haber
L. Feldbrügge
T. Winklmann
S. Werner
J. Pratschke
Moritz Schmelzle
Publication date
01-06-2019
Publisher
Springer Berlin Heidelberg
Published in
Langenbeck's Archives of Surgery / Issue 4/2019
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-019-01790-1

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