Published in:
Open Access
01-12-2024 | Liposarcoma | Case Report
A case of fat-forming solitary fibrous tumor that is prone to be confused with liposarcoma
Authors:
Yi-Dan Ma, Zi-Qing Wu, Xin-Rong Liang, Lin Jing Pi, Meng-Zhen Gong, Yao Tang
Published in:
Diagnostic Pathology
|
Issue 1/2024
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Abstract
Fat-forming solitary fibrous tumor is a rare and specific subtype of solitary fibrous tumor. In this case, a mass of 8.3 cm in diameter was found in a 59-year-old male patient’s right retroperitoneum, as revealed by abdominal contrast-enhanced computed tomography (CT) images. The tumor exhibited a well-circumscribed nature and histological features characterized by a combination of hemangiopericytomatous vasculature and mature adipose tissue, comprising around 70% of the total tumor composition. Immunohistochemistry staining revealed diffuse positive expression of STAT6 and CD34 in the tumor cells. Based on these findings, the final diagnosis was determined to be a fat-forming solitary fibrous tumor located in the retroperitoneum. It is important to consider other potential differential diagnoses, including angiomyolipoma, dedifferentiated liposarcoma, spindle cell lipoma, and atypical lipomatous tumor/well-differentiated liposarcoma.