Skip to main content
Top
Published in: Journal of Medical Case Reports 1/2023

Open Access 01-12-2023 | Liposarcoma | Case report

Mediastinal liposarcoma: a case report and review of the literature

Authors: Jamal Ataya, Ali Alakbar Nahle, Hussein Hamdar, Amjad Sikaria, Younes Souleiman

Published in: Journal of Medical Case Reports | Issue 1/2023

Login to get access

Abstract

Background

Mediastinal Liposarcoma (ML) is an exceedingly rare neoplasm, accounting for less than 1% of all liposarcomas. Surgical resection is the most effective therapeutic modality, while adjuvant radiation therapy may be recommended for unresectable tumors.

Case presentation

This case report presents a rare case of a 52-year-old Syrian male patient with well-differentiated mediastinal liposarcoma (ML) who presented with exertional dyspnea, cough, and weight loss. Imaging studies revealed a large tumor causing extrinsic compression on the right lung, as well as compression of the heart and great vessels. CT-guided biopsy confirmed a diagnosis of well-differentiated liposarcoma, and the patient underwent surgical resection. The patient had a rapid postoperative recovery and was discharged on the fourth day post-operation, displaying an excellent postoperative status. The patient was followed up for 3 months postoperatively with no recurrence.

Conclusion

This report highlights the significance of incorporating ML into the differential diagnosis of mediastinal masses, particularly in individuals presenting with exertional dyspnea and weight loss. Furthermore, this report provides a comprehensive review of previously reported cases of ML in the medical literature.
Literature
4.
go back to reference Barbetakis N, Samanidis G, Paliouras D, Boukovinas I, Kiziridou A, Tsilikas C. A rare cause of mediastinal mass: Primary liposarcoma. J BUON. 2008;13(3):429–31.PubMed Barbetakis N, Samanidis G, Paliouras D, Boukovinas I, Kiziridou A, Tsilikas C. A rare cause of mediastinal mass: Primary liposarcoma. J BUON. 2008;13(3):429–31.PubMed
9.
go back to reference Luna-Martínez J, Molina-Ramírez D, Mata-Quintero CJ, García-Arrona LR, Peña-Rosas DP, Mondragón-Pinzón EE. Liposarcoma mixoide de mediastino anterior. Reporte de caso y revisión de la bibliografía [Myxoid liposarcoma of the anterior mediastinum. A case report and bibliography review]. Cir Cir. 2014;82(2):177–182. [Spanish] Luna-Martínez J, Molina-Ramírez D, Mata-Quintero CJ, García-Arrona LR, Peña-Rosas DP, Mondragón-Pinzón EE. Liposarcoma mixoide de mediastino anterior. Reporte de caso y revisión de la bibliografía [Myxoid liposarcoma of the anterior mediastinum. A case report and bibliography review]. Cir Cir. 2014;82(2):177–182. [Spanish]
12.
go back to reference Khan MH, Kashif R, Rahim Khan HA, Fatimi SH. Myxoid liposarcoma originating in the anterior mediastinum. J Ayub Med Coll Abbottabad. 2016;28(4):818–20.PubMed Khan MH, Kashif R, Rahim Khan HA, Fatimi SH. Myxoid liposarcoma originating in the anterior mediastinum. J Ayub Med Coll Abbottabad. 2016;28(4):818–20.PubMed
15.
go back to reference Mansuet-Lupo A, Lococo F, Larousserie F, Alifano M, Saliceti R. Dedifferentiated primary mediastinal liposarcoma mimicking a thymic tumor. Pathologica. 2017;109(4):401–4.PubMed Mansuet-Lupo A, Lococo F, Larousserie F, Alifano M, Saliceti R. Dedifferentiated primary mediastinal liposarcoma mimicking a thymic tumor. Pathologica. 2017;109(4):401–4.PubMed
Metadata
Title
Mediastinal liposarcoma: a case report and review of the literature
Authors
Jamal Ataya
Ali Alakbar Nahle
Hussein Hamdar
Amjad Sikaria
Younes Souleiman
Publication date
01-12-2023
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2023
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-023-04121-7

Other articles of this Issue 1/2023

Journal of Medical Case Reports 1/2023 Go to the issue