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Published in: Head and Neck Pathology 1/2020

01-03-2020 | Lipoma | Case Report

Primary Pleomorphic Lipoma of the Parotid Gland with Prominent Myxoid Change: Report of a Rare Case Mimicking Carcinoma Ex Pleomorphic Adenoma on Fine Needle Aspiration Cytology

Authors: Giap Hean Goh, Thomas Choudary Putti, Raymond Ngo, Abbas Agaimy, Fredrik Petersson

Published in: Head and Neck Pathology | Issue 1/2020

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Abstract

We present a case of a primary 2.5 cm pleomorphic lipoma of the right parotid gland with prominent myxoid change which on FNA displayed features that mimicked a carcinoma or sarcoma ex pleomorphic adenoma. The patient was a 79 year old man with no oncological history or tumor elsewhere. On immunohistochemistry the neoplastic cells strongly expressed CD34. There was no expression of retinoblastoma protein, smooth muscle actin, S100-protein or cytokeratins (AE1/3 and CAM5.2). The Ki-67 proliferation index was low (< 2%). Fluorescence in situ hybridization was negative for MDM2 gene amplification.
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Metadata
Title
Primary Pleomorphic Lipoma of the Parotid Gland with Prominent Myxoid Change: Report of a Rare Case Mimicking Carcinoma Ex Pleomorphic Adenoma on Fine Needle Aspiration Cytology
Authors
Giap Hean Goh
Thomas Choudary Putti
Raymond Ngo
Abbas Agaimy
Fredrik Petersson
Publication date
01-03-2020
Publisher
Springer US
Published in
Head and Neck Pathology / Issue 1/2020
Electronic ISSN: 1936-0568
DOI
https://doi.org/10.1007/s12105-018-00998-9

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