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Drug Safety
Published in: Drug Safety 7/2010

01-07-2010 | Current Opinion

Recurrence of Adverse Drug Reactions following Inappropriate Re-Prescription

Better Documentation, Availability of Information and Monitoring are Needed

Authors: Dr Carolien M. J. van der Linden, Paul A. F. Jansen, Rob J. van Marum, René J. E. Grouls, Erik H. M. Korsten, Antoine C. G. Egberts

Published in: Drug Safety | Issue 7/2010

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Abstract

Adverse drug reactions (ADRs) are a common, and often preventable, cause of hospital admission, especially in the elderly, and can occur during hospitalization.

In this current opinion article, we present three cases of recurrence of a serious ADR due to re-prescription of a withdrawn medication that highlight the need for a system to prevent the undesirable re-prescription of medications withdrawn because of an ADR. In addition, we describe an electronic system that could help prevent undesirable re-prescription following an ADR. Such a system should document ADRs systematically at the patient level, make this information available to relevant healthcare providers and the patient, and flag re-prescription of the offending drug. The effectiveness and cost effectiveness of such a system would need to be determined.

Literature
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  2. Leendertse AJ, Egberts ACG, Stoker LJ, et al. Frequency of and risk factors for preventable medication-related hospital admissions in the Netherlands. Arch Intern Med 2008; 168(17): 1890–6PubMedView Article
  3. Mannesse CK, Derkx FH, de Ridder MA, et al. Adverse drug reactions in elderly patients as contributing factor for hospital admission: cross sectional study. BMJ 1997; 315: 1057–8PubMedView Article
  4. van der Linden CMJ, Kerskes CH, Bijl AMH, et al. Represcription after adverse drug reaction in the elderly: a descriptive study. Arch Intern Med 2006; 166: 1666–7PubMedView Article
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Metadata
Title
Recurrence of Adverse Drug Reactions following Inappropriate Re-Prescription
Better Documentation, Availability of Information and Monitoring are Needed
Authors
Dr Carolien M. J. van der Linden
Paul A. F. Jansen
Rob J. van Marum
René J. E. Grouls
Erik H. M. Korsten
Antoine C. G. Egberts
Publication date
01-07-2010
Publisher
Springer International Publishing
Published in
Drug Safety / Issue 7/2010
Print ISSN: 0114-5916
Electronic ISSN: 1179-1942
DOI
https://doi.org/10.2165/11532350-000000000-00000

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