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Sports Medicine
Published in: Sports Medicine 4/2006

01-04-2006 | Review Article

Oxidative Stress

Relationship with Exercise and Training

Authors: Julien Finaud, Gérard Lac, Edith Filaire

Published in: Sports Medicine | Issue 4/2006

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Abstract

Free radicals are reactive compounds that are naturally produced in the human body. They can exert positive effects (e.g. on the immune system) or negative effects (e.g. lipids, proteins or DNA oxidation). To limit these harmful effects, an organism requires complex protection — the antioxidant system. This system consists of antioxidant enzymes (catalase, glutathione peroxidase, superoxide dismutase) and non-enzymatic antioxidants (e.g. vitamin E [tocopherol], vitamin A [retinol], vitamin C [ascorbic acid], glutathione and uric acid). An imbalance between free radical production and antioxidant defence leads to an oxidative stress state, which may be involved in aging processes and even in some pathology (e.g. cancer and Parkinson’s disease). Physical exercise also increases oxidative stress and causes disruptions of the homeostasis. Training can have positive or negative effects on oxidative stress depending on training load, training specificity and the basal level of training. Moreover, oxidative stress seems to be involved in muscular fatigue and may lead to overtraining.
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Metadata
Title
Oxidative Stress
Relationship with Exercise and Training
Authors
Julien Finaud
Gérard Lac
Edith Filaire
Publication date
01-04-2006
Publisher
Springer International Publishing
Published in
Sports Medicine / Issue 4/2006
Print ISSN: 0112-1642
Electronic ISSN: 1179-2035
DOI
https://doi.org/10.2165/00007256-200636040-00004

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