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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 13/2022

04-08-2022 | Solid Tumor | ASO Author Reflections

ASO Author Reflections: How Immunotherapy Could Change the Management of Responsive Solid Tumors

Authors: Nicholas D. Klemen, MD, Michael I. D’Angelica, MD

Published in: Annals of Surgical Oncology | Issue 13/2022

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Excerpt

Responses to immunotherapy are unique from what has historically been observed with cytotoxic chemotherapy. The latter rarely mediate durable tumor regression, although it can eradicate occult micrometastatic disease in some patients. By contrast, when immunotherapy results in a complete radiographic response, it is often durable and recurrence is the exception. These results demonstrate the ablative potential of immunotherapy in well-selected patients, which can sterilize (or at least durably suppress) even large volumes of metastatic disease. …
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Verschoor YL, van den Berg J, Beets G, et al. Neoadjuvant nivolumab, ipilimumab, and celecoxib in MMR-proficient and MMR-deficient colon cancers: final clinical analysis of the NICHE study. J Clin Oncol. 2022;40(16 Suppl):3511.CrossRef
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Metadata
Title
ASO Author Reflections: How Immunotherapy Could Change the Management of Responsive Solid Tumors
Authors
Nicholas D. Klemen, MD
Michael I. D’Angelica, MD
Publication date
04-08-2022
Publisher
Springer International Publishing
Keyword
Solid Tumor
Published in
Annals of Surgical Oncology / Issue 13/2022
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-022-12167-y

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