Published in:
01-03-2021 | Nephrectomy | Sarcoma
Nephrectomy for Retroperitoneal Sarcoma: Stay Calm and (Cautiously) Carry On
Authors:
Mark Fairweather, MD, Chandrajit P. Raut, MD, MSc
Published in:
Annals of Surgical Oncology
|
Issue 3/2021
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Excerpt
Soft tissue sarcomas are a rare group of tumors, each with their own inherent biologic behavior driven by histologic subtype and location. There have been significant advancements in recent years in understanding the unique tumor biology of those histologic subtypes arising within the retroperitoneum from studies conducted through multiinstitutional and international collaboration. Surgery, often involving en bloc multivisceral resection, remains the cornerstone treatment for localized retroperitoneal sarcomas (RPS). The extent of resection has been a source of debate over recent years. At a minimum, the extent of resection should be guided by anatomic considerations and histologic-specific tumor biology that ultimately dictates the risk of adjacent organ infiltration, patterns of local/distant failure, and survival. …