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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 3/2020

01-12-2020 | Hashimoto Thyroiditis | ASO Author Reflections

ASO Author Reflection: Getting Closer to Solving the Mystery Behind Mastalgia: Evening Primrose Oil and Factors Affecting Its Therapeutic Efficacy

Authors: Fatih Levent Balci, MD, Cihan Uras, MD, Sheldon Feldman, MD

Published in: Annals of Surgical Oncology | Special Issue 3/2020

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Excerpt

Many drugs have been used in trying to solve the mystery behind mastalgia, which causes discomfort for almost all women. Several studies have been conducted to explain the cause of breast pain, and different opinions have been reported; however, the etiology and optimal treatment of mastalgia are still inadequately defined. It is proposed that saturated fatty acid esters may cause mastalgia via hypersensitivity of the breast epithelium to circulating hormones. Taking evening primrose oil (EPO) orally is believed to restore saturated/unsaturated fatty acid balance and decrease sensitivity to steroidal hormones or prolactin causing mastalgia.1‐3 The aim of this study was to determine the effectiveness of EPO, administered orally, on the severity of cyclical or non-cyclical mastalgia, and any factors that may affect its treatment efficacy. …
Literature
1.
Morrow M. The evaluation of common breast problems. Am Fam Phys. 2000;61(8):2371-8–85-8.
2.
Pruthi S, Wahner-Roedler DL, Torkelson CJ, et al. Vitamin E and evening primrose oil for management of cyclical mastalgia: a randomized pilot study. Altern Med Rev. 2010;15(1):59–67.PubMed
3.
Gateley CA, Maddox PR, Pritchard GA, et al. Plasma fatty acid profiles in benign breast disorders. Br J Surg. 1992;79(5):407–09.CrossRef
4.
Metadata
Title
ASO Author Reflection: Getting Closer to Solving the Mystery Behind Mastalgia: Evening Primrose Oil and Factors Affecting Its Therapeutic Efficacy
Authors
Fatih Levent Balci, MD
Cihan Uras, MD
Sheldon Feldman, MD
Publication date
01-12-2020
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue Special Issue 3/2020
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-020-09032-1

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