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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 7/2020

01-07-2020 | Hepatocellular Carcinoma | ASO Author Reflections

ASO Author Reflections: Recurrence Patterns and Outcomes After Resection of Hepatocellular Carcinoma Within and Beyond the Barcelona Clinic Liver Cancer Criteria

Authors: Diamantis I. Tsilimigras, MD, Timothy M. Pawlik, MD, MPH, PhD

Published in: Annals of Surgical Oncology | Issue 7/2020

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Excerpt

Although the Barcelona Clinic Liver Cancer (BCLC) staging system has been endorsed by both the European Association for the Study of the Liver 1 and the American Association for the Study of Liver Diseases,2 investigators have advocated for extending the resection criteria to select patients with BCLC-B or even BCLC-C hepatocellular carcinoma (HCC).3,4 Nevertheless, outcomes and patterns of recurrence after resection of HCC within and beyond the BCLC criteria have not been well defined. By utilizing an international, multi-institutional cohort, we sought to determine the outcomes as well as the patterns of recurrence after resection of HCC within (i.e., BCLC-0/A) and beyond (i.e., BCLC-B/C) the BCLC criteria.5 …
Literature
1.
European Association for the Study of the Liver. EASL clinical practice guidelines: management of hepatocellular carcinoma. J Hepatol. 2018;69:182–236.CrossRef
2.
Marrero JA, Kulik LM, Sirlin CB, et al. Diagnosis, staging, and management of hepatocellular carcinoma: 2018 practice guidance by the American Association for the Study of Liver Diseases. Hepatology. 2018;68:723–50.CrossRef
3.
Tsilimigras DI, Bagante F, Sahara K, et al. Prognosis after resection of Barcelona Clinic Liver Cancer (BCLC) stage 0, A, and B hepatocellular carcinoma: a comprehensive assessment of the current BCLC classification. Ann Surg Oncol. 2019;26:3693–700.CrossRef
4.
Tsilimigras DI, Mehta R, Moris D, et al. Utilizing machine learning for pre- and postoperative assessment of patients undergoing resection for BCLC-0, A and B hepatocellular carcinoma: implications for resection beyond the BCLC guidelines. Ann Surg Oncol. 2020;27:866–74.CrossRef
5.
Metadata
Title
ASO Author Reflections: Recurrence Patterns and Outcomes After Resection of Hepatocellular Carcinoma Within and Beyond the Barcelona Clinic Liver Cancer Criteria
Authors
Diamantis I. Tsilimigras, MD
Timothy M. Pawlik, MD, MPH, PhD
Publication date
01-07-2020
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue 7/2020
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-020-08455-0

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