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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 3/2018

01-12-2018 | ASO Author Reflections

ASO Author Reflections: Acellular Dermal Matrix Reduces Myofibroblasts in Capsule Tissue

Authors: Il-Kug Kim, MD, PhD, Ung Sik Jin, MD, PhD

Published in: Annals of Surgical Oncology | Special Issue 3/2018

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Excerpt

Capsular contracture is a major complication of implant-based breast reconstruction. Recent studies have shown that use of acellular dermal matrices (ADM) for coverage of breast implants decreased or prevented capsular contractures. Moyer et al.1 performed histopathological analysis of native capsules and ADM capsules in both nonirradiated and irradiated patients. They observed significant differences in cellular infiltration and elastin distribution only. Other researchers have also investigated the histological differences between subpectoral and ADM capsules and the mechanism by which the ADM reduces capsule formation around the breast implant. However, the mechanism remains unclear. …
Literature
1.
Moyer HR, Pinell-White X, Losken A. The effect of radiation on acellular dermal matrix and capsule formation in breast reconstruction: clinical outcomes and histologic analysis. Plast Reconstr Surg. 2014;133:214–21.CrossRefPubMed
2.
Kim IK, Park SO, Chang H, Jin US. Inhibition mechanism of acellular dermal matrix on capsule formation in expander-implant breast reconstruction after postmastectomy radiotherapy. Ann Surg Oncol. 2018;25:2279–87.CrossRefPubMed
Metadata
Title
ASO Author Reflections: Acellular Dermal Matrix Reduces Myofibroblasts in Capsule Tissue
Authors
Il-Kug Kim, MD, PhD
Ung Sik Jin, MD, PhD
Publication date
01-12-2018
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue Special Issue 3/2018
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-018-6916-5

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