Skip to main content
Top
Published in: Annals of Surgical Oncology 3/2018

01-12-2018 | ASO Author Reflections

ASO Author Reflections: Hypothyroidism and Wound Healing After Salvage Laryngectomy

Authors: Andrew J. Rosko, MD, Matthew E. Spector, MD, FACS

Published in: Annals of Surgical Oncology | Special Issue 3/2018

Login to get access

Excerpt

The treatment of laryngeal squamous cell carcinoma has shifted toward radiotherapy (RT) or chemoradiotherapy (CRT) with the goal of organ preservation and similar survival to primary laryngectomy.1 Recurrence after treatment requires salvage laryngectomy. Radiation predisposes patients to impaired healing, and pharyngocutaneous fistula develops in 30–75% of patients. Fistula increases short- and long-term morbidity for the laryngectomy patient.2
Literature
1.
go back to reference Raja S. Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. N Engl J Med. 1991;324:1685–1690.CrossRef Raja S. Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. N Engl J Med. 1991;324:1685–1690.CrossRef
2.
go back to reference Hier M, Black MJ, Lafond G. Pharyngo-cutaneous fistulas after total laryngectomy: incidence, etiology, and outcome analysis. J Otolaryngol. 1993;22:164–166.PubMed Hier M, Black MJ, Lafond G. Pharyngo-cutaneous fistulas after total laryngectomy: incidence, etiology, and outcome analysis. J Otolaryngol. 1993;22:164–166.PubMed
3.
go back to reference Miller MC, Agrawal A. Hypothyroidism in postradiation head and neck cancer patients: incidence, complications, and management. Curr Opin Otolaryngol Head Neck Surg. 2009;17:111–115.CrossRefPubMed Miller MC, Agrawal A. Hypothyroidism in postradiation head and neck cancer patients: incidence, complications, and management. Curr Opin Otolaryngol Head Neck Surg. 2009;17:111–115.CrossRefPubMed
4.
go back to reference Turner SL, Tiver KW, Boyages SC. Thyroid dysfunction following radiotherapy for head and neck cancer. Int J Radiat Oncol Biol Phys. 1995;31:279–283.CrossRefPubMed Turner SL, Tiver KW, Boyages SC. Thyroid dysfunction following radiotherapy for head and neck cancer. Int J Radiat Oncol Biol Phys. 1995;31:279–283.CrossRefPubMed
5.
go back to reference Rosko, A.J., Birkeland, A.C., Bellile, E. et al. Hypothyroidism and wound healing after salvage laryngectomy. Ann Surg Oncol. 2018; 25: 1288–1295.CrossRefPubMed Rosko, A.J., Birkeland, A.C., Bellile, E. et al. Hypothyroidism and wound healing after salvage laryngectomy. Ann Surg Oncol. 2018; 25: 1288–1295.CrossRefPubMed
Metadata
Title
ASO Author Reflections: Hypothyroidism and Wound Healing After Salvage Laryngectomy
Authors
Andrew J. Rosko, MD
Matthew E. Spector, MD, FACS
Publication date
01-12-2018
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue Special Issue 3/2018
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-018-6873-z

Other articles of this Special Issue 3/2018

Annals of Surgical Oncology 3/2018 Go to the issue