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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 3/2018

01-12-2018 | ASO Author Reflections

The Intraoperative Portable Gamma Camera Is an Important Adjunct to the Gamma Probe in Identifying Melanoma Sentinel Lymph Nodes

Author: Stanley P. Leong, MD

Published in: Annals of Surgical Oncology | Special Issue 3/2018

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Excerpt

The false-negative rate (FNR) for melanoma sentinel lymph node (SLN) surgery ranges between 5.6 and 21%.1,2 Preoperative lymphoscintigraphy with single-photon emission computed tomography and computed tomography (SPECT/CT) imaging, intraoperative localization of SLNs, and pathologic examination of these lymph nodes are important steps for the optimal evaluation of SLNs. Missing SLNs intraoperatively is a major cause for an increasing FNR in melanoma SLN surgery. The goal of this study was to show whether Sentinella (Sentinella S102, Oncovision S.A., Valencia, Spain), an intraoperative portable gamma camera (PGC), can increase identification of SLNs found by gamma probe (GP) used in the conventional surgical approach. Furthermore, we wanted to know whether any additional SLNs identified by the PGC  might contain micrometastasis.2 …
Literature
1.
Tardelli E, Mazzarri S, Rubello D, et al. Sentinel lymph node biopsy in cutaneous melanoma: standard and new technical procedures and clinical advances: a systematic review of the literature. Clin Nucl Med. 2016;41:e498–507.CrossRefPubMed
2.
3.
McMasters KM, Reintgen DS, Ross MI, et al. Sentinel lymph node biopsy for melanoma: how many radioactive nodes should be removed? Ann Surg Oncol. 2001;8:192–197.CrossRefPubMed
4.
Liu L-C, Parrett BM, Jenkins T, et al. Selective sentinel lymph node dissection for melanoma: importance of harvesting nodes with lower radioactive counts without the need for blue dye. Ann Surg Oncol. 2011;18:2919–24.CrossRefPubMed
5.
Faries MB, Thompson JF, Cochran AJ, et al. Completion dissection or observation for sentinel-node metastasis in melanoma. N Engl J Med. 2017;376:2211–22.CrossRefPubMedCentralPubMed
Metadata
Title
The Intraoperative Portable Gamma Camera Is an Important Adjunct to the Gamma Probe in Identifying Melanoma Sentinel Lymph Nodes
Author
Stanley P. Leong, MD
Publication date
01-12-2018
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue Special Issue 3/2018
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-018-6755-4

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