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Published in: Annals of Surgical Oncology 3/2014

01-03-2014 | Hepatobiliary Tumors

Does Anti-HBV Therapy Benefit the Prognosis of HBV-Related Hepatocellular Carcinoma Following Hepatectomy?

Authors: Liang-He Yu, Nan Li, Jie Shi, Wei-Xing Guo, Meng-Chao Wu, Shu-Qun Cheng

Published in: Annals of Surgical Oncology | Issue 3/2014

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Abstract

The Hepatitis B virus (HBV) is an important etiological factor for hepatocarcinogenesis, because HBV DNA load and HBV reactivation are major risks that influence the long-term survival of hepatocellular carcinoma (HCC) patients who underwent hepatectomy and, thus, may cause postoperative liver function deterioration, tumor recurrence, and reduce patient’s overall survival. However, anti-HBV therapy can suppress HBV replication, improve the remnant liver function, render patients better able to tolerate HCC treatments, and may even improve their prognosis. In this paper, an anti-HBV therapy that benefits the prognosis of HBV-related HCC following hepatectomy is reviewed.
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Metadata
Title
Does Anti-HBV Therapy Benefit the Prognosis of HBV-Related Hepatocellular Carcinoma Following Hepatectomy?
Authors
Liang-He Yu
Nan Li
Jie Shi
Wei-Xing Guo
Meng-Chao Wu
Shu-Qun Cheng
Publication date
01-03-2014
Publisher
Springer US
Published in
Annals of Surgical Oncology / Issue 3/2014
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-013-3320-z

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