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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 6/2011

01-06-2011 | Head and Neck Oncology

Contribution of Computed Tomography to Ultrasound in Predicting Lateral Lymph Node Metastasis in Patients with Papillary Thyroid Carcinoma

Authors: Jung Hyun Yoon, MD, Ji Youn Kim, MD, Hee Jung Moon, MD, Ji Hyun Youk, MD, PhD, Eun Joo Son, MD, PhD, Eun-Kyung Kim, MD, Kyung Hwa Han, MS, Jin Young Kwak, MD

Published in: Annals of Surgical Oncology | Issue 6/2011

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Abstract

Background

To evaluate the most accurate criteria using ultrasound (US) and contrast-enhanced computed tomography (CT) in predicting lateral lymph node metastasis in patients with papillary thyroid carcinoma (PTC).

Methods

A total of 122 lateral cervical lymph nodes of 113 patients diagnosed with PTC underwent preoperative US-guided fine-needle aspiration biopsy (US-FNAB) and CT. Degree of enhancement (DOE) was calculated by the differences of Hounsfield units (HU) between the lymph node and the ipsilateral sternocleiomastoideus muscle. Standard reference was set by surgical pathology results. Diagnostic performances of US, CT, and cutoff value for DOE were analyzed.

Results

Seventy lymph nodes (57.4%) were metastases, and 52 (42.6%) were benign. The cutoff value of DOE on CT was 35.7 HU. Diagnostic performance of CT including DOE of 35.7 HU was lower than US, but without significance (P = 0.321). When any suspicious CT feature was combined with the combination of suspicious US features, values of the area under the receiver operating characteristic curve decreased compared to the combinations of suspicious US features alone, 0.785 to 0.741, respectively (P = 0.225).

Conclusions

Contrast-enhanced CT does not greatly improve diagnostic values of US in the diagnosis of metastatic lateral cervical lymph nodes in patients with PTC.
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Metadata
Title
Contribution of Computed Tomography to Ultrasound in Predicting Lateral Lymph Node Metastasis in Patients with Papillary Thyroid Carcinoma
Authors
Jung Hyun Yoon, MD
Ji Youn Kim, MD
Hee Jung Moon, MD
Ji Hyun Youk, MD, PhD
Eun Joo Son, MD, PhD
Eun-Kyung Kim, MD
Kyung Hwa Han, MS
Jin Young Kwak, MD
Publication date
01-06-2011
Publisher
Springer-Verlag
Published in
Annals of Surgical Oncology / Issue 6/2011
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-010-1527-9

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