Skip to main content
Top
Published in: Annals of Surgical Oncology 1/2008

01-01-2008 | Bone and Soft Tissue Sarcomas

Predictors of Complications and Outcomes of External Hemipelvectomy Wounds: Account of 160 Consecutive Cases

Authors: Alex Senchenkov, MD, Steven L. Moran, MD, Paul M. Petty, MD, James Knoetgen III, MD, Ricky P. Clay, MD, Uldis Bite, MD, Sunni A. Barnes, PhD, Franklin H. Sim, MD

Published in: Annals of Surgical Oncology | Issue 1/2008

Login to get access

Abstarct

Background

Hemipelvectomy has high wound complication rates. This study aimed to determine variables that may influence hemipelvectomy wound morbidity.

Methods

The records of 160 consecutive hemipelvectomy patients were reviewed with a focus on demographics, treatment, and surgical techniques. Multivariate analysis was used to determine risk factors for postoperative hemipelvectomy wound infection and flap necrosis.

Results

There were 31 standard, 62 modified, and 67 extended hemipelvectomy patients in whom 19 contiguous visceral, 62 spinal, 4 contralateral pelvic resections, and 1 contralateral hemipelvectomy were performed. Hospital mortality rate was 5%, and overall morbidity was 54%. Wound complications such as infection (39%) and flap necrosis (26%) were the most common. For modified, standard, and extended hemipelvectomies, rates of wound infection were 29%, 34%, and 51% (P = .036) and rates of flap necrosis were 16%, 25%, and 35% (P = .046), respectively. Longer operative time and increased complexity were associated with higher wound infection and flap necrosis rates. The hemipelvectomy flap design did not influence the frequency of wound infection (P = .173) or flap necrosis (P = .098). Common iliac vessel ligation was the most statistically significant predictor of flap necrosis and was associated with the 2.7-fold increase in flap necrosis rate (P = .001) in patients undergoing posterior flap hemipelvectomy.

Conclusions

External hemipelvectomy has low mortality but high morbidity. Postoperative wound infection and flap necrosis are multifactorial events related to length and extent of operation. Level of vascular ligation strongly influenced flap necrosis rate for posterior flap hemipelvectomy.
Literature
1.
go back to reference Higinbotham NL, Marcove RC, Casson P. Hemipelvectomy: a clinical study of 100 cases with five-year-follow-up on 60 patients. Surgery 1966; 59:706–8PubMed Higinbotham NL, Marcove RC, Casson P. Hemipelvectomy: a clinical study of 100 cases with five-year-follow-up on 60 patients. Surgery 1966; 59:706–8PubMed
2.
go back to reference Douglass HO Jr, Razack M, Holyoke ED. Hemipelvectomy. Arch Surg 1975; 110:82–5PubMed Douglass HO Jr, Razack M, Holyoke ED. Hemipelvectomy. Arch Surg 1975; 110:82–5PubMed
3.
go back to reference American Society of Anesthesiologist. New classification of physical status. Anesthesiology 1963; 24:111 American Society of Anesthesiologist. New classification of physical status. Anesthesiology 1963; 24:111
4.
go back to reference Owens WD, Felts JA, Spitznagel EL Jr. ASA physical status classifications: a study of consistency of ratings. Anesthesiology 1978; 49:239–43PubMedCrossRef Owens WD, Felts JA, Spitznagel EL Jr. ASA physical status classifications: a study of consistency of ratings. Anesthesiology 1978; 49:239–43PubMedCrossRef
5.
go back to reference Culver DH, Horan TC, Gaynes RP, et al. Surgical wound infection rates by wound class, operative procedure, and patient risk index. National Nosocomial Infections Surveillance System. Am J Med 1991; 91:152S–7SPubMedCrossRef Culver DH, Horan TC, Gaynes RP, et al. Surgical wound infection rates by wound class, operative procedure, and patient risk index. National Nosocomial Infections Surveillance System. Am J Med 1991; 91:152S–7SPubMedCrossRef
6.
go back to reference Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics 1977; 33:159–74PubMedCrossRef Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics 1977; 33:159–74PubMedCrossRef
7.
go back to reference Miller TR. 100 cases of hemipelvectomy: a personal experience. Surg Clin North Am 1974; 54:905–13PubMed Miller TR. 100 cases of hemipelvectomy: a personal experience. Surg Clin North Am 1974; 54:905–13PubMed
8.
go back to reference Karakousis CP, Emrich LJ, Driscoll DL. Variants of hemipelvectomy and their complications. Am J Surg 1989; 158:404–8PubMedCrossRef Karakousis CP, Emrich LJ, Driscoll DL. Variants of hemipelvectomy and their complications. Am J Surg 1989; 158:404–8PubMedCrossRef
9.
go back to reference Prewitt TW, Alexander HR, Sindelar WF. Hemipelvectomy for soft tissue sarcoma: clinical results in fifty-three patients. Surg Oncol 1995; 4:261–9PubMed Prewitt TW, Alexander HR, Sindelar WF. Hemipelvectomy for soft tissue sarcoma: clinical results in fifty-three patients. Surg Oncol 1995; 4:261–9PubMed
10.
go back to reference King D, Steelquist J. Transiliac amputation. J Bone Joint Surg 1943; 25:352–67 King D, Steelquist J. Transiliac amputation. J Bone Joint Surg 1943; 25:352–67
11.
go back to reference Temple WJ, Mnaymneh W, Ketcham AS. The total thigh and rectus abdominis myocutaneous flap for closure of extensive hemipelvectomy defects. Cancer 1982; 50:2524–8PubMedCrossRef Temple WJ, Mnaymneh W, Ketcham AS. The total thigh and rectus abdominis myocutaneous flap for closure of extensive hemipelvectomy defects. Cancer 1982; 50:2524–8PubMedCrossRef
12.
go back to reference Malawer MM, Sugarbaker PH. Musculoskeletal Cancer Surgery. Vol 1. Dordrecht: luwer Academic Publishers, 2001 Malawer MM, Sugarbaker PH. Musculoskeletal Cancer Surgery. Vol 1. Dordrecht: luwer Academic Publishers, 2001
13.
go back to reference Bowden L, Booher RJ. Surgical considerations in the treatment of sarcoma of the buttock. Cancer 1953; 6:89–99PubMedCrossRef Bowden L, Booher RJ. Surgical considerations in the treatment of sarcoma of the buttock. Cancer 1953; 6:89–99PubMedCrossRef
14.
go back to reference Frey C, Matthews LS, Benjamin H, Fidler WJ. A new technique for hemipelvectomy. Surg Gynecol Obstet 1976; 143:753–6PubMed Frey C, Matthews LS, Benjamin H, Fidler WJ. A new technique for hemipelvectomy. Surg Gynecol Obstet 1976; 143:753–6PubMed
15.
go back to reference Mnaymneh W, Temple W. Modified hemipelvectomy utilizing a long vascular myocutaneous thigh flap. Case report. J Bone Joint Surg Am 1980; 62:1013–5PubMed Mnaymneh W, Temple W. Modified hemipelvectomy utilizing a long vascular myocutaneous thigh flap. Case report. J Bone Joint Surg Am 1980; 62:1013–5PubMed
16.
go back to reference Georgiade N, Pickrell K, Maguire C. Total thigh flaps for extensive decubitus ulcers. Plast Reconstr Surg 1956; 17:220–5CrossRef Georgiade N, Pickrell K, Maguire C. Total thigh flaps for extensive decubitus ulcers. Plast Reconstr Surg 1956; 17:220–5CrossRef
17.
go back to reference Kulaylat MN, Froix A, Karakousis CP. Blood supply of hemipelvectomy flaps: the anterior flap hemipelvectomy. Arch Surg 2001; 136:828–31PubMedCrossRef Kulaylat MN, Froix A, Karakousis CP. Blood supply of hemipelvectomy flaps: the anterior flap hemipelvectomy. Arch Surg 2001; 136:828–31PubMedCrossRef
19.
go back to reference Apffelstaedt JP, Zhang PJ, Driscoll DL, Karakousis CP. Various types of hemipelvectomy for soft tissue sarcomas: complications, survival and prognostic factors. Surg Oncol 1995; 4:217–22PubMedCrossRef Apffelstaedt JP, Zhang PJ, Driscoll DL, Karakousis CP. Various types of hemipelvectomy for soft tissue sarcomas: complications, survival and prognostic factors. Surg Oncol 1995; 4:217–22PubMedCrossRef
20.
go back to reference Apffelstaedt JP, Driscoll DL, Spellman JE, et al. Complications and outcome of external hemipelvectomy in the management of pelvic tumors. Ann Surg Oncol 1996; 3:304–9PubMedCrossRef Apffelstaedt JP, Driscoll DL, Spellman JE, et al. Complications and outcome of external hemipelvectomy in the management of pelvic tumors. Ann Surg Oncol 1996; 3:304–9PubMedCrossRef
21.
go back to reference Karakousis CP. The abdominoinguinal incision: the equivalent of thoracoabdominal incision for the lower quadrants of the abdomen. J Surg Oncol 1998; 69:249–57PubMedCrossRef Karakousis CP. The abdominoinguinal incision: the equivalent of thoracoabdominal incision for the lower quadrants of the abdomen. J Surg Oncol 1998; 69:249–57PubMedCrossRef
22.
go back to reference Karakousis CP. Abdominoinguinal incision and other incisions in the resection of pelvic tumors. Surg Oncol 2000; 9:83–90PubMedCrossRef Karakousis CP. Abdominoinguinal incision and other incisions in the resection of pelvic tumors. Surg Oncol 2000; 9:83–90PubMedCrossRef
24.
go back to reference Workman ML, Bailey DF, Cunningham BL. Popliteal-based filleted lower leg musculocutaneous free-flap coverage of a hemipelvectomy defect. Plast Reconstr Surg 1992; 89:326–9PubMedCrossRef Workman ML, Bailey DF, Cunningham BL. Popliteal-based filleted lower leg musculocutaneous free-flap coverage of a hemipelvectomy defect. Plast Reconstr Surg 1992; 89:326–9PubMedCrossRef
25.
go back to reference Yamamoto Y, Minakawa H, Takeda N. Pelvic reconstruction with a free fillet lower leg flap. Plast Reconstr Surg 1997; 99:1439–41PubMedCrossRef Yamamoto Y, Minakawa H, Takeda N. Pelvic reconstruction with a free fillet lower leg flap. Plast Reconstr Surg 1997; 99:1439–41PubMedCrossRef
26.
go back to reference Butzelaar RM, Fortner JG. Results of hemipelvectomy for soft tissue sarcoma. Neth J Surg 1981; 33:79–82PubMed Butzelaar RM, Fortner JG. Results of hemipelvectomy for soft tissue sarcoma. Neth J Surg 1981; 33:79–82PubMed
27.
go back to reference Capanna R, Manfrini M, Pignatti G, et al. Hemipelvectomy in malignant neoplasms of the hip region. Ital J Orthop Traumatol 1990; 16:425–37PubMed Capanna R, Manfrini M, Pignatti G, et al. Hemipelvectomy in malignant neoplasms of the hip region. Ital J Orthop Traumatol 1990; 16:425–37PubMed
28.
go back to reference Sugarbaker PH, Chretien PA. Hemipelvectomy. In: Sugarbaker PH, Nicholson TH, eds. Atlas of Extremity Sarcoma Surgery. Philadelphia: JB Lippincott, 1984:45–67 Sugarbaker PH, Chretien PA. Hemipelvectomy. In: Sugarbaker PH, Nicholson TH, eds. Atlas of Extremity Sarcoma Surgery. Philadelphia: JB Lippincott, 1984:45–67
29.
go back to reference Dunn DL, Beilman GJ. Surgical infections. In: Brunicardi FC, Andersen DK, Billiar TR, et al, eds. Schwartz’s Principles of Surgery. New York: McGraw-Hill, 2005:108–28 Dunn DL, Beilman GJ. Surgical infections. In: Brunicardi FC, Andersen DK, Billiar TR, et al, eds. Schwartz’s Principles of Surgery. New York: McGraw-Hill, 2005:108–28
30.
go back to reference National Academy of Sciences-National Research Council. Postoperative wound infections: the influence of ultraviolet irradiation of the operating room and of various other factors. Ann Surg 1964; 160(Suppl 2):1–132 National Academy of Sciences-National Research Council. Postoperative wound infections: the influence of ultraviolet irradiation of the operating room and of various other factors. Ann Surg 1964; 160(Suppl 2):1–132
31.
go back to reference Consensus paper on the surveillance of surgical wound infections. The Society for Hospital Epidemiology of America; The Association for Practitioners in Infection Control; The Centers for Disease Control; The Surgical Infection Society. Infect Control Hosp Epidemiol 1992; 13:599–605CrossRef Consensus paper on the surveillance of surgical wound infections. The Society for Hospital Epidemiology of America; The Association for Practitioners in Infection Control; The Centers for Disease Control; The Surgical Infection Society. Infect Control Hosp Epidemiol 1992; 13:599–605CrossRef
32.
go back to reference National Nosocomial Infections Surveillance (NNIS) system report, data summary from January 1992–April 2000, issued June 2000. Am J Infect Control 2000; 28:429–48 National Nosocomial Infections Surveillance (NNIS) system report, data summary from January 1992–April 2000, issued June 2000. Am J Infect Control 2000; 28:429–48
Metadata
Title
Predictors of Complications and Outcomes of External Hemipelvectomy Wounds: Account of 160 Consecutive Cases
Authors
Alex Senchenkov, MD
Steven L. Moran, MD
Paul M. Petty, MD
James Knoetgen III, MD
Ricky P. Clay, MD
Uldis Bite, MD
Sunni A. Barnes, PhD
Franklin H. Sim, MD
Publication date
01-01-2008
Publisher
Springer-Verlag
Published in
Annals of Surgical Oncology / Issue 1/2008
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-007-9672-5

Other articles of this Issue 1/2008

Annals of Surgical Oncology 1/2008 Go to the issue