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01-11-2021 | NSCLC | ASO Author Reflections

ASO Author Reflections: Is Wedge Resection Optimal for Octogenarians with Early-Stage Non-Small-Cell Lung Cancer Compared with Lobectomy/Segmentectomy?

Authors: Takahiro Mimae, MD, PhD, Hisashi Saji, MD, PhD, Morihito Okada, MD, PhD

Published in: Annals of Surgical Oncology | Issue 12/2021

Excerpt

Anatomical resection including segmentectomy and lobectomy would be considered a standard treatment for patients with early-stage non-small cell lung cancer (NSCLC) if the results of the ongoing, prospective, randomized Japanese Clinical Oncology Group 0802/West Japan Oncology Group 4607L (JCOG0802/WJOG4607L)1 and Cancer and Leukemia Group B (CALGB) 1405032 trials were positive. This treatment strategy is the same for patients aged ≥ 80 and < 80 years. However, patients are assumed to be at higher risk for anatomical resection if aged ≥ 80 years. Thus, whether anatomical or wedge resection would be more appropriate for populations aged ≥ 80 years has remained undetermined. …

Nakamura K, Saji H, Nakajima R, Okada M, Asamura H, Shibata T, et al. A phase III randomized trial of lobectomy versus limited resection for small-sized peripheral non-small cell lung cancer (JCOG0802/WJOG4607L). Jpn J Clin Oncol. 2010;40:271–4.CrossRef

Kohman LJ, Gu L, Altorki N, Scalzetti E, Veit LJ, Wallen JM, et al. Biopsy first: lessons learned from cancer and leukemia group B (CALGB) 140503. J Thorac Cardiovasc Surg. 2017;153:1592–7.CrossRef

Mimae T, Miyata Y, Tsutani Y, Imai K, Ito H, Nakayama H, et al. Wedge resection as an alternative treatment for octogenarian and older patients with early-stage non-small-cell lung cancer. Jpn J Clin Oncol. 2020;50:1051–7.CrossRef

Mimae T, Saji H, Nakamura H, et al. Survival of octogenarians with early-stage non-small-cell lung cancer is comparable between wedge resection and lobectomy/segmentectomy: JACS1303. Ann Surg Oncol. 2021. https://doi.org/10.1245/s10434-021-09835-w.CrossRefPubMed

Title: ASO Author Reflections: Is Wedge Resection Optimal for Octogenarians with Early-Stage Non-Small-Cell Lung Cancer Compared with Lobectomy/Segmentectomy?
Authors: Takahiro Mimae, MD, PhD
Hisashi Saji, MD, PhD
Morihito Okada, MD, PhD
Publication date: 01-11-2021
Publisher: Springer International Publishing
Keywords: NSCLC
Lung Cancer
Lung Cancer
NSCLC
Lung Cancer
Published in: Annals of Surgical Oncology / Issue 12/2021
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI: https://doi.org/10.1245/s10434-021-09860-9

2024 ASCO Annual Meeting

Springer Medicine

ASO Author Reflections: Is Wedge Resection Optimal for Octogenarians with Early-Stage Non-Small-Cell Lung Cancer Compared with Lobectomy/Segmentectomy?

Excerpt

2024 ASCO Annual Meeting

Springer Medicine

Excerpt

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