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01-06-2014 | Gastrointestinal Oncology

Postgastrectomy Syndrome Assessment Scale (PGSAS)-45 and Changes in Body Weight are Useful Tools for Evaluation of Reconstruction Methods Following Distal Gastrectomy

Authors: Masanori Terashima, MD, PhD, FACS, Kazuaki Tanabe, MD, PhD, Masashi Yoshida, MD, PhD, FACS, Hiroshi Kawahira, MD, PhD, Takao Inada, MD, PhD, Hiroshi Okabe, MD, PhD, FACS, Takashi Urushihara, MD, PhD, Yoshiyuki Kawashima, MD, PhD, Norimasa Fukushima, MD, PhD, Koji Nakada, MD

Published in: Annals of Surgical Oncology | Special Issue 3/2014

Abstract

Background

Billroth-I (BI) and Roux-en-Y (RY) are well-known reconstruction methods that are conducted following distal gastrectomy. However, the relative merits of these 2 methods are not well documented. The newly developed Postgastrectomy Syndrome Assessment Scale (PGSAS)-45 is an integrated questionnaire consisting of 45 items, including 8 items from the 8-Item Short-Form Health Survey (SF-8), 15 items from the Gastrointestinal Symptom Rating Scale, and 22 items selected by gastric surgeons. Postoperative QOL ratings were evaluated for each reconstruction method using PGSAS-45.

Methods

The PGSAS-45 questionnaire was distributed to 2,922 patients who underwent gastrectomies at 52 medical institutions. Among the questionnaires distributed, 2520 (86 %) were retrieved and 2368 (81 %) met eligibility requirements. Statistical analyses were conducted to compare 1,384 of the eligible questionnaires, including responses from patients who underwent BI (n = 909) and RY (n = 475) procedures.

Results

BI procedures were associated with significantly longer postoperative periods, a significantly greater size of gastric remnants, and a higher frequency of laparoscopic approaches and celiac branch preservation. Postoperative QOL analysis indicated that BI procedures resulted in significantly lower postoperative weight loss and significantly higher esophageal reflux symptoms than RY procedures. There was no significant difference between the two groups on other outcome measures.

Conclusions

Although weight loss was significantly lower following BI procedures, esophageal reflux symptoms were significantly higher. Either BI or RY procedures may be recommended based on the individual patient’s condition after distal gastrectomy. The newly developed QOL questionnaire, PGSAS-45 and changes in body weight proved useful for evaluation of QOL following gastrectomy.

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Title: Postgastrectomy Syndrome Assessment Scale (PGSAS)-45 and Changes in Body Weight are Useful Tools for Evaluation of Reconstruction Methods Following Distal Gastrectomy
Authors: Masanori Terashima, MD, PhD, FACS
Kazuaki Tanabe, MD, PhD
Masashi Yoshida, MD, PhD, FACS
Hiroshi Kawahira, MD, PhD
Takao Inada, MD, PhD
Hiroshi Okabe, MD, PhD, FACS
Takashi Urushihara, MD, PhD
Yoshiyuki Kawashima, MD, PhD
Norimasa Fukushima, MD, PhD
Koji Nakada, MD
Publication date: 01-06-2014
Publisher: Springer US
Published in: Annals of Surgical Oncology / Issue Special Issue 3/2014
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI: https://doi.org/10.1245/s10434-014-3583-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Postgastrectomy Syndrome Assessment Scale (PGSAS)-45 and Changes in Body Weight are Useful Tools for Evaluation of Reconstruction Methods Following Distal Gastrectomy

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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