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Published in: Neurological Research and Practice 1/2019

Open Access 01-12-2019 | Stroke | Research article

Inpatient TIA and stroke care in adult patients in Germany - retrospective analysis of nationwide administrative data sets of 2011 to 2017

Authors: Jens Eyding, Dirk Bartig, Ralph Weber, Aristeidis H. Katsanos, Christian Weimar, Werner Hacke, Christos Krogias

Published in: Neurological Research and Practice | Issue 1/2019

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Abstract

Background

Comprehensive administrative data on TIA and stroke cases and treatment modalities are fundamental for improving structural conditions and adjusting future strategies of stroke care.

Methods

The nationwide administrative database (German federal statistical office) was used to extract all adult inpatient TIA and stroke cases and corresponding procedural codes for the period 2011–2017. Numbers were specified according to age, sex, stroke unit (SU) and critical care treatment (ICU), early transfer, and in-hospital mortality.

Findings

Inpatient adult TIA/stroke cases increased from annually 102,406 / 250,199 (2011) to 106,245 / 264,208 (2017). 84% of strokes were ischemic (AIS) also having the highest relative increase most likely due to more accurate coding within the time period, 68.2% of AIS were treated on SUs. 78% of hemorrhagic strokes were intracerebral hematomas (ICH; rather than subarachnoid hemorrhages [SAH]). Hemorrhagic strokes were increasingly treated on SUs (32.6% [2011], 37.8% [2017]). 68.8% of SAH were treated on ICUs (ICH:36.3%, AIS:10.3%). Early transfer in AIS increased (2.0 to 3.1%). Hemorrhagic strokes were associated with higher in-hospital mortality (SAH:19.6%, ICH:28.2%, AIS:7.3%).

Interpretation

The absolute increase of strokes presumably reflects the aging society and more awareness for cerebrovascular disease. The relative increase of AIS may be attributable to an increased neurological expertise. The increasing amount of early transfers in AIS reflects new specialized treatment options. Our findings reflect the need for structural adjustments in inpatient stroke care.
Appendix
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Footnotes
1
International Statistical Classification of Diseases and Related Health Problems 10th revision, German modification
 
2
The German coding system and the ICD version remained unchanged during the analyzed time period except for implementation of the OPS code 8-98f for elaborated intensive care in 2013. Until 2012, all patients treated on an intensive care unit were coded with OPS 8–980.
 
3
Only few (< 600 per year) children and adolescents < 20 years were hospitalized for TIA or stroke between 2011 and 2017 and therefore excluded from statistical analysis.
 
4
Including G45.3 (amaurosis fugax) and G45.4 (transient global amnesia); G45.3 accounted for about 3.000 cases and G45.4 for about 7.000 cases.
 
Literature
1.
go back to reference Feigin, V. L., Forouzanfar, M. H., Krishnamurthi, R., et al. (2014). Global burden of diseases, injuries, and risk factors study 2010 (GBD 2010) and the GBD stroke experts group. Global and regional burden of stroke during 1990-2010: Findings from the global burden of disease study 2010. Lancet., 383, 245–254.CrossRef Feigin, V. L., Forouzanfar, M. H., Krishnamurthi, R., et al. (2014). Global burden of diseases, injuries, and risk factors study 2010 (GBD 2010) and the GBD stroke experts group. Global and regional burden of stroke during 1990-2010: Findings from the global burden of disease study 2010. Lancet., 383, 245–254.CrossRef
2.
go back to reference Krishnamurthi, R. V., Moran, A. E., Feigin, V. L., et al. (2015). Stroke prevalence, mortality and disability-adjusted life years in adults aged 20-64 years in 1990-2013: Data from the global burden of disease 2013 study. Neuroepidemiology., 45, 190–202.CrossRef Krishnamurthi, R. V., Moran, A. E., Feigin, V. L., et al. (2015). Stroke prevalence, mortality and disability-adjusted life years in adults aged 20-64 years in 1990-2013: Data from the global burden of disease 2013 study. Neuroepidemiology., 45, 190–202.CrossRef
3.
go back to reference GBD 2016 DALYs and HALE Collaborators. (2017). Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet, 390, 1260–1344.CrossRef GBD 2016 DALYs and HALE Collaborators. (2017). Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet, 390, 1260–1344.CrossRef
4.
go back to reference The GBD 2016 Lifetime risk of stroke collaborators. (2018). Global, regional, and country-specific lifetime risks of stroke, 1990 and 2016. N Engl J med, 379, 2429–2437.CrossRef The GBD 2016 Lifetime risk of stroke collaborators. (2018). Global, regional, and country-specific lifetime risks of stroke, 1990 and 2016. N Engl J med, 379, 2429–2437.CrossRef
5.
go back to reference Béjot, Y., Bailly, H., Graber, M., et al. (2019). Impact of the ageing population on the burden of stroke: The Dijon stroke registry. Neuroepidemiology, 52, 78–85.CrossRef Béjot, Y., Bailly, H., Graber, M., et al. (2019). Impact of the ageing population on the burden of stroke: The Dijon stroke registry. Neuroepidemiology, 52, 78–85.CrossRef
6.
go back to reference Bergström, L., Irewall, A. L., Söderström, L., Ögren, J., Laurell, K., & Mooe, T. (2017). One-year incidence, time trends, and predictors of recurrent ischemic stroke in Sweden from 1998 to 2010 an observational study. Stroke., 48, 2046–2051.CrossRef Bergström, L., Irewall, A. L., Söderström, L., Ögren, J., Laurell, K., & Mooe, T. (2017). One-year incidence, time trends, and predictors of recurrent ischemic stroke in Sweden from 1998 to 2010 an observational study. Stroke., 48, 2046–2051.CrossRef
7.
go back to reference Sedova, P., Brown, R. D., Zvolsky, M., et al. (2017). Incidence of hospitalized stroke in the Czech Republic: The National Registry of hospitalized patients. Journal of Stroke and Cerebrovascular Diseases, 26, 979–986.CrossRef Sedova, P., Brown, R. D., Zvolsky, M., et al. (2017). Incidence of hospitalized stroke in the Czech Republic: The National Registry of hospitalized patients. Journal of Stroke and Cerebrovascular Diseases, 26, 979–986.CrossRef
8.
go back to reference Weber, R., Eyding, J., Kitzrow, M., et al. (2019). Distribution and evolution of acute interventional ischemic stroke treatment in Germany from 2010 to 2016. Neurological Research and Practise, 1, 4.CrossRef Weber, R., Eyding, J., Kitzrow, M., et al. (2019). Distribution and evolution of acute interventional ischemic stroke treatment in Germany from 2010 to 2016. Neurological Research and Practise, 1, 4.CrossRef
10.
go back to reference The Global Burden of Disease Stroke Expert Group. (2012). Methodology of the global and regional burden of stroke study. Neuroepidemiology, 38, 30–40.CrossRef The Global Burden of Disease Stroke Expert Group. (2012). Methodology of the global and regional burden of stroke study. Neuroepidemiology, 38, 30–40.CrossRef
11.
go back to reference de Rooij, N. K., Linn, F. H., van der Plas, J. A., Algra, A., & Rinkel, G. J. (2007). Incidence of subarachnoid haemorrhage: A systematic review with emphasis on region, age, gender and time trends. Journal of Neurology, Neurosurgery, and Psychiatry, 78, 1365–1372.CrossRef de Rooij, N. K., Linn, F. H., van der Plas, J. A., Algra, A., & Rinkel, G. J. (2007). Incidence of subarachnoid haemorrhage: A systematic review with emphasis on region, age, gender and time trends. Journal of Neurology, Neurosurgery, and Psychiatry, 78, 1365–1372.CrossRef
12.
go back to reference Mohan, K. M., Wolfe, C. D., Rudd, A. G., Heuschmann, P. U., Kolominsky-Rabas, P. L., & Grieve, A. P. (2011). Risk and cumulative risk of stroke recurrence: A systematic review and meta-analysis. Stroke, 42, 1489–1494.CrossRef Mohan, K. M., Wolfe, C. D., Rudd, A. G., Heuschmann, P. U., Kolominsky-Rabas, P. L., & Grieve, A. P. (2011). Risk and cumulative risk of stroke recurrence: A systematic review and meta-analysis. Stroke, 42, 1489–1494.CrossRef
13.
go back to reference Tu, K., Wang, M., Young, J., et al. (2013). Validity of administrative data for identifying patients who have had a stroke or transient ischemic attack using EMRALD as a reference standard. The Canadian Journal of Cardiology, 29, 1388–1394.CrossRef Tu, K., Wang, M., Young, J., et al. (2013). Validity of administrative data for identifying patients who have had a stroke or transient ischemic attack using EMRALD as a reference standard. The Canadian Journal of Cardiology, 29, 1388–1394.CrossRef
16.
go back to reference Sacco, S., Pistoia, F., & Carolei, A. (2013). Stroke tracked by administrative coding data: Is it fair? Stroke., 44, 1766–1768.CrossRef Sacco, S., Pistoia, F., & Carolei, A. (2013). Stroke tracked by administrative coding data: Is it fair? Stroke., 44, 1766–1768.CrossRef
17.
go back to reference van Gijn, J., Kerr, R. S., & Rinkel, G. J. (2007). Subarachnoid haemorrhage. Lancet., 369, 306–318.CrossRef van Gijn, J., Kerr, R. S., & Rinkel, G. J. (2007). Subarachnoid haemorrhage. Lancet., 369, 306–318.CrossRef
18.
go back to reference Nimptsch, U., & Mansky, T. (2012). Trends in acute inpatient stroke care in Germany - an observational study using administrative hospital data from 2005-2010. Deutsches Ärzteblatt International, 109, 885–892.PubMedPubMedCentral Nimptsch, U., & Mansky, T. (2012). Trends in acute inpatient stroke care in Germany - an observational study using administrative hospital data from 2005-2010. Deutsches Ärzteblatt International, 109, 885–892.PubMedPubMedCentral
Metadata
Title
Inpatient TIA and stroke care in adult patients in Germany - retrospective analysis of nationwide administrative data sets of 2011 to 2017
Authors
Jens Eyding
Dirk Bartig
Ralph Weber
Aristeidis H. Katsanos
Christian Weimar
Werner Hacke
Christos Krogias
Publication date
01-12-2019
Publisher
BioMed Central
Published in
Neurological Research and Practice / Issue 1/2019
Electronic ISSN: 2524-3489
DOI
https://doi.org/10.1186/s42466-019-0044-y

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