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Clinical and Translational Medicine
Published in: Clinical and Translational Medicine 1/2018

Open Access 01-12-2018 | Review

Lipidomics unveils the complexity of the lipidome in metabolic diseases

Authors: Todd A. Lydic, Young-Hwa Goo

Published in: Clinical and Translational Medicine | Issue 1/2018

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Abstract

Dysregulation of lipid metabolism is responsible for pathologies of human diseases including metabolic diseases. Recent advances in lipidomics analysis allow for the targeted and untargeted identification of lipid species and for their quantification in normal and diseased conditions. Herein, this review provides a brief introduction to lipidomics, highlights its application to characterize the lipidome at the cellular and physiological levels under different biological conditions, and discusses the potential for the use of lipidomics in the discovery of biomarkers.
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Metadata
Title
Lipidomics unveils the complexity of the lipidome in metabolic diseases
Authors
Todd A. Lydic
Young-Hwa Goo
Publication date
01-12-2018
Publisher
Springer Berlin Heidelberg
Published in
Clinical and Translational Medicine / Issue 1/2018
Electronic ISSN: 2001-1326
DOI
https://doi.org/10.1186/s40169-018-0182-9

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